ID   A6BE65_9FIRM            Unreviewed;       680 AA.
AC   A6BE65;
DT   24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2007, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   RecName: Full=UvrD-like helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51198};
GN   ORFNames=DORLON_00581 {ECO:0000313|EMBL:EDM63904.1};
OS   Dorea longicatena DSM 13814.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX   NCBI_TaxID=411462 {ECO:0000313|EMBL:EDM63904.1, ECO:0000313|Proteomes:UP000004016};
RN   [1] {ECO:0000313|EMBL:EDM63904.1, ECO:0000313|Proteomes:UP000004016}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13814 {ECO:0000313|EMBL:EDM63904.1,
RC   ECO:0000313|Proteomes:UP000004016};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EDM63904.1, ECO:0000313|Proteomes:UP000004016}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13814 {ECO:0000313|EMBL:EDM63904.1,
RC   ECO:0000313|Proteomes:UP000004016};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Dorea longicatena (DSM 13814).";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDM63904.1}.
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DR   EMBL; AAXB02000002; EDM63904.1; -; Genomic_DNA.
DR   RefSeq; WP_006426604.1; NZ_DS264392.1.
DR   AlphaFoldDB; A6BE65; -.
DR   eggNOG; COG3973; Bacteria.
DR   HOGENOM; CLU_010312_4_0_9; -.
DR   Proteomes; UP000004016; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          203..537
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         224..231
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   680 AA;  79441 MW;  2A381EA3B0A99E9F CRC64;
     MTELDLTDGK IFLNKVTEKI RTRLAEVDAS IEAGQKDIQS MNEYYWENYT EMDEYGYENY
     DNQQALLHQV NDNQEKLKMQ HRLRKMLEAP FFGRVDFIYD GEDEPEIFYI GIGNFAERTG
     MLPLIYDWRA PVSGLFYDYD KGPGSYEAPA GLIEGEIAAK WQYKVKNGKM VYAFESDTKI
     DDDILKQELG TNSDVQLKNI VRTIQKEQNA IIRNTHDRIL AIQGAAGSGK TSVALHRIAY
     LLYHDREHLK SSNVLILSPN SVFSDYISHI LPELGEENIQ EMSFDLFAYR ELKGIVPDCE
     DRYDQLERTM KLQDPYLTER FEEKQLEGFV GMMEGFLARL EDELMDFRAI EYKGIQKTKE
     ELINLFYFKF QNAPLLSRVD AIRDYCVDEY ETLLGRDLSE EELLIVQEKF DKMYVTKDIY
     KIYGWLLEEC GYPSLPDVEY EKRKLEYEDV FPVLYLKYRL TGKAVHNHIK HLVIDEMQDY
     SYLQYVILNQ IFKCRMTILG DKAQTLDEQM RDVLQFLPGV FDQKIRKIVM NKSYRNTMEI
     ARYAEKLTGV KDVELLKRHG KEVVEEQFQT EDAVLDEILS KAKLGEDEYE TAAIITMTEA
     EASTLYQILK ARGEEVHYID RNSSVFKKGL TVTTFYLAKG LEFDQVFGVF QDSGNPMLNQ
     AKYICATRAL HELYMYQITE
//