ID A6BKA1_9FIRM Unreviewed; 508 AA.
AC A6BKA1;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Putative DNA modification/repair radical SAM protein {ECO:0000313|EMBL:EDM61872.1};
GN ORFNames=DORLON_02750 {ECO:0000313|EMBL:EDM61872.1};
OS Dorea longicatena DSM 13814.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX NCBI_TaxID=411462 {ECO:0000313|EMBL:EDM61872.1, ECO:0000313|Proteomes:UP000004016};
RN [1] {ECO:0000313|EMBL:EDM61872.1, ECO:0000313|Proteomes:UP000004016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13814 {ECO:0000313|EMBL:EDM61872.1,
RC ECO:0000313|Proteomes:UP000004016};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDM61872.1, ECO:0000313|Proteomes:UP000004016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13814 {ECO:0000313|EMBL:EDM61872.1,
RC ECO:0000313|Proteomes:UP000004016};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Dorea longicatena (DSM 13814).";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDM61872.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAXB02000021; EDM61872.1; -; Genomic_DNA.
DR RefSeq; WP_006427662.1; NZ_DS264403.1.
DR AlphaFoldDB; A6BKA1; -.
DR GeneID; 64017306; -.
DR eggNOG; COG4277; Bacteria.
DR HOGENOM; CLU_033784_0_0_9; -.
DR Proteomes; UP000004016; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 1.10.150.320; Photosystem II 12 kDa extrinsic protein; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR023874; DNA_rSAM_put.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR010994; RuvA_2-like.
DR NCBIfam; TIGR03916; rSAM_link_UDG; 1.
DR PANTHER; PTHR21180; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR21180:SF9; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01102; Uncharacterised_Radical_SAM_Su; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 68..202
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|Pfam:PF04055"
FT REGION 244..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..265
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 57296 MW; 03D52E1819C7F6F0 CRC64;
MNIEIKNSNY TTQEKLQILA DAAKYDVACT SSGSSRRGKK GELGNTEACG ICHSFAADGR
CISLLKILMT NHCAYDCKYC INRASNDVKR ATFTPEEICE LTIEFYKRNY IEGLFLSSGV
LKNPTYTMEK MCETLLLLRT KYHFNGYIHV KTIPGASDEL LAAAGYLADR ISVNLELPTE
EGLRTLAPNK TMKTILNPMG KVQNTIAAHR MAIGKTAYME RSRGNQLLNN GIFSEISKRN
YRESLEEKKK TDRLSDGKDG TLPSQKEMGR VDGLLTWDNA YQLAPHDMSG LKRRFAPAGQ
STQMIIGATG ESDYTLLQTT QQLYQGFDLK RVFYSAYIPL NEDDALPGLG TPTPLLREHR
LYQADWLLRF YGFQAGELLS EEKPDFNELI DPKCDWALRH LEQFPVEIET ASYARLLRVP
GIGPKSASRI THARRYGRLD FASLKKMGVV LKRAHYFITC GGKQMYHTPV EASYIMRQLV
SVDKKDVWNI EHSNESYVQL SLADFGIG
//
