ID A6CVX2_9VIBR Unreviewed; 781 AA.
AC A6CVX2;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN ORFNames=VSAK1_22829 {ECO:0000313|EMBL:EDL55424.1};
OS Vibrio mediterranei AK1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=391591 {ECO:0000313|EMBL:EDL55424.1, ECO:0000313|Proteomes:UP000003769};
RN [1] {ECO:0000313|EMBL:EDL55424.1, ECO:0000313|Proteomes:UP000003769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK1 {ECO:0000313|EMBL:EDL55424.1,
RC ECO:0000313|Proteomes:UP000003769};
RA Rosenberg E., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 33 family.
CC {ECO:0000256|ARBA:ARBA00009348}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL55424.1}.
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DR EMBL; ABCH01000002; EDL55424.1; -; Genomic_DNA.
DR RefSeq; WP_006069484.1; NZ_ABCH01000002.1.
DR AlphaFoldDB; A6CVX2; -.
DR Proteomes; UP000003769; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR GO; GO:0033691; F:sialic acid binding; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR015344; VCNA_lectin-like_dom.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR Pfam; PF09264; Sial-lect-inser; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..781
FT /note="exo-alpha-sialidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002693567"
FT DOMAIN 65..218
FT /note="Vibrio cholerae neuraminidase lectin-like"
FT /evidence="ECO:0000259|Pfam:PF09264"
FT DOMAIN 347..544
FT /note="Vibrio cholerae neuraminidase lectin-like"
FT /evidence="ECO:0000259|Pfam:PF09264"
FT DOMAIN 557..747
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
SQ SEQUENCE 781 AA; 84122 MW; 91E47F6AC35F6356 CRC64;
MVFRKNRQAV WLVMAIGTAP LANAELFDYM ATTDPVKDQP SEQGWIADHS QSGSGALSTV
DGVTAWVAQG EGGRAQWKTV LSDALKSQAT NYGWRLSTEM RVVSGGMITN YYADGSQRVL
PILSINSAGE LVVEFEGRSG TTVLATGAAA TDYHKYELVF HPGDNPNASF YFDGQLILDQ
ISPSPTSQNM LVWGNGSTYT DGVSAYKNIE FEVQGDVIFN GPDRIPSLVA STETPGVVTA
FAEKRVGGGD PGSTANTNDI IARVSTDSGV TWNTELNLTE QINANDDYDF SDPRPIYDSA
SDSVVVSYVR WPTDAAQNGD KIKSWMPSGV FYSTYDIATS NWLAPVDVTH QVKEHSYQIA
GWGGSELYSK SATLNSNQDW QLNATLRIFD GAANRIQAAD GARTFVVTFA VDPSGQLTAQ
LNGESSPVVV ALSSGDVYGF HQYQIAYSAL SNQASLLVDG NTLASWSGET SSSNLVEFGN
ADSSVDGRIH LQDIALEQSG VTLVSLDAAY LAQQDPASTT TDLEQLGWSK QKSGNTMSFY
GHASVNPGPG HGIQLERQQA IAGSHNGRLI YPAITLDRYF LNVMSVYSDD GGQNWQTGAS
LPLPYRWKSA SSLETLEPSE SDLVELDNGH LLLTARLDFN KTVSGVNYGP RQQFLSEDGG
KTWAMLSGNN ADVFPGISSG TVDASITRFE EADGSRYLLF TNPQGSPSGA SNRQDLGLWF
SFDEGNSWKG PIQLVEGASA YSDIYQLDAE TAIVIVETNS SNMRILRVPV TLLKQKALAL
P
//
