ID A6D0R7_9VIBR Unreviewed; 570 AA.
AC A6D0R7;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Putative cation efflux system transmembrane protein {ECO:0000313|EMBL:EDL53820.1};
GN ORFNames=VSAK1_10298 {ECO:0000313|EMBL:EDL53820.1};
OS Vibrio mediterranei AK1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=391591 {ECO:0000313|EMBL:EDL53820.1, ECO:0000313|Proteomes:UP000003769};
RN [1] {ECO:0000313|EMBL:EDL53820.1, ECO:0000313|Proteomes:UP000003769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK1 {ECO:0000313|EMBL:EDL53820.1,
RC ECO:0000313|Proteomes:UP000003769};
RA Rosenberg E., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL53820.1}.
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DR EMBL; ABCH01000013; EDL53820.1; -; Genomic_DNA.
DR RefSeq; WP_006071360.1; NZ_ABCH01000013.1.
DR AlphaFoldDB; A6D0R7; -.
DR Proteomes; UP000003769; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 6.10.140.730; -; 1.
DR Gene3D; 2.40.50.320; Copper binding periplasmic protein CusF; 2.
DR InterPro; IPR021647; CusF_Ec.
DR InterPro; IPR042230; CusF_sf.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR045800; HMBD.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF15; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR Pfam; PF11604; CusF_Ec; 2.
DR Pfam; PF16576; HlyD_D23; 1.
DR Pfam; PF19335; HMBD; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000313|EMBL:EDL53820.1};
KW Transmembrane {ECO:0000313|EMBL:EDL53820.1}.
FT DOMAIN 48..74
FT /note="Heavy metal binding"
FT /evidence="ECO:0000259|Pfam:PF19335"
FT DOMAIN 111..319
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 570 AA; 62054 MW; 5D0407B65BFB4D2F CRC64;
MKTLNVALLA LAVGAGIGVL VAPYVGGHNM AEASDENAST KGAKEPLYWV APMDPNYQRD
QPGKSPMGMD LIPVYADDLN GGNEKPGTVN INPAVENNLG VKTEPVKLAK LSPRIETVGY
IAFDESRLWQ TNVRVAGWVE KLYINAVGER VNKGDVLFKL YSPELVKAQE ELLNAHRTGR
SSLVKGATER LISLGVDRAQ INQIVKQGKA SQTIDIKALG NGVVATLNIR EGGYLSPAQS
VISAGPIDEV WVDAEVFERQ AEWIKAGSQA TMTLDALSGR EWQGEIDYVY PILDPATRTL
RVRLKFANPD HQLKPNMFAN IALQPKTEQA VLTIPRSSVI RSGGMTRVVL SEGGGKYRSA
RIDIGREARD RVEVLAGLTT SDKVVTSAQF MLDSESSQSA DLSRINGVEL PAEAVWAQGE
ITSVMAGHNM LTINHQPVPE WDWPGMTMDF TVDKGVNLNT LQSGQQVEFE MAKTDSGQYA
IIDLKVSDKR VVEKVWVQGD ITMLMADFGM ITLSHNAVAE WGWEAGEMNF TSQGDVDLTG
FAEGETVRFL VTKQGSDYVL IDLQRGGGQP
//
