ID A6DP68_9BACT Unreviewed; 472 AA.
AC A6DP68;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Iduronate-2-sulfatase {ECO:0000313|EMBL:EDM26600.1};
GN ORFNames=LNTAR_02292 {ECO:0000313|EMBL:EDM26600.1};
OS Lentisphaera araneosa HTCC2155.
OC Bacteria; Lentisphaerota; Lentisphaeria; Lentisphaerales; Lentisphaeraceae;
OC Lentisphaera.
OX NCBI_TaxID=313628 {ECO:0000313|EMBL:EDM26600.1, ECO:0000313|Proteomes:UP000004947};
RN [1] {ECO:0000313|EMBL:EDM26600.1, ECO:0000313|Proteomes:UP000004947}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2155 {ECO:0000313|EMBL:EDM26600.1,
RC ECO:0000313|Proteomes:UP000004947};
RX PubMed=20363947; DOI=10.1128/JB.00208-10;
RA Thrash J.C., Cho J.C., Vergin K.L., Morris R.M., Giovannoni S.J.;
RT "Genome sequence of Lentisphaera araneosa HTCC2155T, the type species of
RT the order Lentisphaerales in the phylum Lentisphaerae.";
RL J. Bacteriol. 192:2938-2939(2010).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDM26600.1}.
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DR EMBL; ABCK01000015; EDM26600.1; -; Genomic_DNA.
DR RefSeq; WP_007279651.1; NZ_ABCK01000015.1.
DR AlphaFoldDB; A6DP68; -.
DR STRING; 313628.LNTAR_02292; -.
DR eggNOG; COG3119; Bacteria.
DR OrthoDB; 5901192at2; -.
DR Proteomes; UP000004947; Unassembled WGS sequence.
DR GO; GO:0004423; F:iduronate-2-sulfatase activity; IEA:InterPro.
DR CDD; cd16030; iduronate-2-sulfatase; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR035874; IDS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR45953; IDURONATE 2-SULFATASE; 1.
DR PANTHER; PTHR45953:SF1; IDURONATE 2-SULFATASE; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000004947};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 23..374
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 472 AA; 53692 MW; 02AA2506FA46F420 CRC64;
MNKVFAICIF AMIANLCAEN KYNVLMICVD DLRNSLGCYG NKDVISPNFD KLASESVAFD
HHYVQVPTCG ASRYALLTGL RPQNKQSMGN GAFKQLSRTQ LDGAQTIPEL FKRSNYLTSV
IGKVSHTADG RNYAYNGKGN GSDELPFAWD WKKTPFGPWK RGWGVFFAYA DGKHREDGSG
YKPRMEFKDL EDEELPDGLS ANEAIRQLDK LKDKRFFLSL GFYKPHLPFV APKKYWDMYD
GVDINLAPHD KKGETAYWHG SGEFYKYQGD KTKPLSTEEQ VKHRRAYYAC ISYVDAQLGK
VMQRLKDLGL DKNTIVVLWS DHGWHLGDHQ IWGKHNLHEQ ALKSPFMIRV PDIKGKMSSA
VVETTDLFPT LIELCQLTFN KLSQPLSGQS LVPILNSVDT LGRDSALSFW GKAVSLRNKN
YRLIATKGKK DEYSKIELYD HRIDPNESKN IAQQNPEVVD QLLKIIKKEN KL
//
