ID A6E8S9_9SPHI Unreviewed; 1859 AA.
AC A6E8S9;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Putative outer membrane protein {ECO:0000313|EMBL:EDM38409.1};
GN ORFNames=PBAL39_02302 {ECO:0000313|EMBL:EDM38409.1};
OS Pedobacter sp. BAL39.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=391596 {ECO:0000313|EMBL:EDM38409.1, ECO:0000313|Proteomes:UP000003664};
RN [1] {ECO:0000313|EMBL:EDM38409.1, ECO:0000313|Proteomes:UP000003664}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BAL39 {ECO:0000313|EMBL:EDM38409.1,
RC ECO:0000313|Proteomes:UP000003664};
RA Hagstrom A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protease inhibitor I39 (alpha-2-
CC macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
CC {ECO:0000256|ARBA:ARBA00010556}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDM38409.1}.
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DR EMBL; ABCM01000002; EDM38409.1; -; Genomic_DNA.
DR RefSeq; WP_008238578.1; NZ_ABCM01000002.1.
DR STRING; 391596.PBAL39_02302; -.
DR eggNOG; COG2373; Bacteria.
DR OrthoDB; 9767116at2; -.
DR Proteomes; UP000003664; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd02891; A2M_like; 1.
DR Gene3D; 1.50.10.20; -; 1.
DR Gene3D; 2.60.40.1930; -; 1.
DR Gene3D; 2.60.40.3710; -; 1.
DR InterPro; IPR011625; A2M_N_BRD.
DR InterPro; IPR047565; Alpha-macroglob_thiol-ester_cl.
DR InterPro; IPR011626; Alpha-macroglobulin_TED.
DR InterPro; IPR021868; Alpha_2_Macroglob_MG3.
DR InterPro; IPR041203; Bact_A2M_MG5.
DR InterPro; IPR041462; Bact_A2M_MG6.
DR InterPro; IPR041246; Bact_MG10.
DR InterPro; IPR001599; Macroglobln_a2.
DR InterPro; IPR002890; MG2.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR40094; ALPHA-2-MACROGLOBULIN HOMOLOG; 1.
DR PANTHER; PTHR40094:SF1; UBIQUITIN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00207; A2M; 1.
DR Pfam; PF07703; A2M_BRD; 1.
DR Pfam; PF17973; bMG10; 1.
DR Pfam; PF11974; bMG3; 1.
DR Pfam; PF17972; bMG5; 1.
DR Pfam; PF17962; bMG6; 1.
DR Pfam; PF01835; MG2; 1.
DR Pfam; PF07678; TED_complement; 1.
DR SMART; SM01360; A2M; 1.
DR SMART; SM01359; A2M_N_2; 1.
DR SMART; SM01419; Thiol-ester_cl; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000003664}.
FT DOMAIN 994..1136
FT /note="Alpha-2-macroglobulin bait region"
FT /evidence="ECO:0000259|SMART:SM01359"
FT DOMAIN 1200..1289
FT /note="Alpha-2-macroglobulin"
FT /evidence="ECO:0000259|SMART:SM01360"
SQ SEQUENCE 1859 AA; 206800 MW; 9AF503E3B10F2E83 CRC64;
MKFNPSLFIQ KNKTGIIAAI FILLVLGVSA VFLFKKKRPD DYNQAYSKYI ESYTSGTISK
KSLIRVHLTN QVKTMSDIGV PDNRDLFSFS PSIKGKSYWI DAQTVEFRPD ENMEPGETYE
ATFNLQKVTE TEEAQKEFEF SFKVINPGML LTQNGLVSQN NTSLDFMKVS GEVTTSDAEE
GKQIEQSLKI DFDQNLKVKW QHNPAKNSSS FTIDSIRKGK SEKMLKLNWS GKSINADNKG
EETLQVPAVG VFKILDIRAV QDLEDYALVQ FSEPVNVAQD LNGLLSLGEL TDLRFTIDGS
QVKIYAPTPL EGNYTLTVNE GIENINSKVL QTGKTANVVF ENKNPSVTIA GSGSIIPNSG
KLVLPFEAVN LKAVDVTIIK VYENNIPQFF QTNGYRDGSE LRRVGKPVLQ KTIRLDEDRS
LDLHKKHRFT LDLDKIMKTE PGAMYRVTIG FRQEYNAFKC AEIQDDAAES DGEYYGYGEK
IDEDDDFWER YNSYYPERYS WSDRDNPCTP SYYTNDKWAS RNLIASNIGL IAKRGNDNSM
LIIATDLLTA KTMSGVTLEL LDYQRQVIHT IQTDGDGMAA FDLKRKPFLL IAKHGDERGY
LKLDDGSSLP LSRFDVGGDV VQNGLKGFIY GERGVWRPGD SVFLSFILED KLKKLPGAYP
VTFELYNPQG QLVKRTINGK PLNGFYAFRT ATESTAPTGN WLAKVKAGGS TFSKTIKIET
VMPNRLKINF DIGNRPYLGI GASSTASLAA NWLFGAPGKH LKAKVDVNLN TMETTFKGFS
GYQFDNPTVS FESQVKTIFE GTLNENGTAV VNTNLNENNS APGMLRANFT TKVFEAGGNF
SIDNFSIPYH VYDNYYGVKT PEGDKLSGML VTGKDHEIDI VNVDRNGALL KGYKTVEVEL
YKVQWRWWWE QDNESYLANF TQNSYNKLIK KANVALSNGK GKWNLRIDEP EWGRYLILVR
GSNGGHVTGK SVYIDWPGWA QREQGNNPTE ASMLSFTANK TKFKVGEEIV LTIPSGKGGR
ALISIENGSK VLKTFWTDTE AGQTQVKFKA EKDMAPNVFA NVTLLQPHAQ TANDLPIRMY
GAIPLLVEDP QTILKPVIRM ADKIKPETES SLTVSEQNGK AMTYTIAIVD EGLLDLTRFK
TPDPHGIFYA REGLGVKTWD LFDYVLGAWG GNLERILSIG GDGSINKNLN PAKANRFVPV
VKYMGPFTIA KGESKTHRFK LPQYIGAVRA MVVAGQDGAY GVAEKSVQVK KPLMLLATLP
RVIGPGERFT LPATVFATEK NLRKVTLQLQ TTNLQVAGSK VQQLQFNQPG EQMAYYEITV
PEITGVAKLK LIAKSGAEQT SYDVELDIRN PNPYVTNVLS AIVNPGENWS TGYQPVGMAG
TNSGSLELSS IPPVNLKKRL SYLMQYPHGC VEQTTSSVFP QLFLDKLSPM TEQQKANKER
NVKAGINRLK GFQTTDGGLA YWPGSPSSDE WGSNYAGHFL VEAQEAGYTL PVGMIDELLR
YLKVKAANWS PNSTNFYGGD LSQSYRLYVL ALAKRPEMAA MNRLRGFQYL SVSAKWRLAA
AYKLAGQTEA ANNLIKGLTF TIEPYQQLGG TYGSDLRDQA MILETMTLLG RKADAAKLIQ
PLATRLGQNE WYSTQTTAYS LLAVAKFCGA NAGSNSLKYD FTIDGKKGSV NTKQFLSTNN
LTFKGSSVSV SNTGDRVLFA RIILQGQPSA GQNDFLPNNA DALDMDVNYK LLNGKVLDPS
TLKQGTDFYA EVTIKNPGKM GYYEQMALTQ IFPSGWEIIN TRLNDNESII ASSPYTYRDI
RDDRVFTYFN LREFEAVTYK VLLNASYIGK YYLSAVQCEA MYNNNITATA SGKWVQVIK
//
