ID A6EQ22_9BACT Unreviewed; 652 AA.
AC A6EQ22;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:EDM44291.1};
GN ORFNames=SCB49_04660 {ECO:0000313|EMBL:EDM44291.1};
OS unidentified eubacterium SCB49.
OC Bacteria; Bacteroidota; environmental samples.
OX NCBI_TaxID=50743 {ECO:0000313|EMBL:EDM44291.1, ECO:0000313|Proteomes:UP000003659};
RN [1] {ECO:0000313|EMBL:EDM44291.1, ECO:0000313|Proteomes:UP000003659}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCB49 {ECO:0000313|EMBL:EDM44291.1,
RC ECO:0000313|Proteomes:UP000003659};
RA Hagstrom A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDM44291.1}.
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DR EMBL; ABCO01000004; EDM44291.1; -; Genomic_DNA.
DR AlphaFoldDB; A6EQ22; -.
DR STRING; 50743.SCB49_04660; -.
DR Proteomes; UP000003659; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR41523:SF7; ETHYLENE RESPONSE SENSOR PROTEIN; 1.
DR PANTHER; PTHR41523; TWO-COMPONENT SYSTEM SENSOR PROTEIN; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07568; HisKA_2; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EDM44291.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003659};
KW Transferase {ECO:0000313|EMBL:EDM44291.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 407..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 457..531
FT /note="Signal transduction histidine kinase subgroup 2
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07568"
FT DOMAIN 556..640
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
SQ SEQUENCE 652 AA; 74714 MW; 0312AC3A925B7046 CRC64;
MKWLLLFFIS FFTSITIAQN KRIKKTYQKE LDSVIKISEA KTNAEEKINT LCGYVSSTRY
TKDMKVLIEL SEKIARTSNQ DDLLATSYYY TANYYYYNAQ LDSALIYVNK SRPLINDQKQ
PLLRSFLTET ESGIYRMQGN NPLAIATLIK SKSLLDKVDT LKLNDLEKGR YRNTVLSSIN
SLANYYNSIE EYEKAESYYN QGYNSSIQNK LNTPAGVFMT NKGDLYLNTK QYDKALIAFE
EGKKLKILGK APQRMIANSD LNLGIAHTQL GNYALAENIL TETIAFYKEQ ENHVKLGQAY
SYRGELYIKK NSFNQAIKDC ENGKNLSQKT NTLELLPQAC NCLYTSYKAL GKIELALSNY
EQFVRANDSI FNEKNIKKQT EQELQYEFSK TEELKNAEIA ARKNQSLLYS ILAIIGFLFA
AFLGFFFYKN RKKNILLAKQ KKLLEATVDE KNILLRETHH RVKNSFQMVS SLLFIQSETS
QNNEAKLAIK EAQNRVRSMV LIHQKLYSKD QLVGIDAQEY IEDFTKDIIE SHQFETTKLN
YEINAEKLIL SIETITPLGL ILNELITNVL KHAFKPVTKN SLLQINFFRN NDALILEVID
NGVGMPTSIK ETSFGIELID ALSKKLKAKR SHKTRSPKGT VASVVIKRFE VL
//
