ID A6GS32_9BURK Unreviewed; 754 AA.
AC A6GS32;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:EDM82997.1};
GN ORFNames=LMED105_11945 {ECO:0000313|EMBL:EDM82997.1};
OS Limnobacter sp. MED105.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Limnobacter.
OX NCBI_TaxID=391597 {ECO:0000313|EMBL:EDM82997.1, ECO:0000313|Proteomes:UP000010322};
RN [1] {ECO:0000313|EMBL:EDM82997.1, ECO:0000313|Proteomes:UP000010322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MED105 {ECO:0000313|EMBL:EDM82997.1,
RC ECO:0000313|Proteomes:UP000010322};
RA Pinhassi J., Pedros-Alio C., Ferriera S., Johnson J., Kravitz S.,
RA Beeson K., Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDM82997.1}.
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DR EMBL; ABCT01000011; EDM82997.1; -; Genomic_DNA.
DR AlphaFoldDB; A6GS32; -.
DR STRING; 391597.LMED105_11945; -.
DR OrthoDB; 9802500at2; -.
DR Proteomes; UP000010322; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010322};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 383..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 498..630
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 754 AA; 82430 MW; 6B523B676CE3F007 CRC64;
MSKLIKSWRK IAGKAFRIGV GFSFTAVALL HVLGFAPSEV VKRLDYLVYD VRLRAEAQLP
ELDPRIVIVD IDEQSLSEVG RWPWSRDVVA KLVVELTDRL GAAAVGFDIV FAEPQQSDAL
LALDTIIENK PALGSQLQEM RSGIQAQFDR DAQLAQVLAD RPVVLGYYLN QDATALSGAL
PPALFKKSQL GELSLDSTSW QGYGGNIPVL QKNAEGGYFN PIVDEDGTVR SIPLIAQFND
AYYQSFALGT LRRALGNPQV IPVFPEGVPD DYGAVELIAL RSPEVELDIP VERGLLTRVH
FRAKGGPNAG GYRYVSAADV LAGALKPEDI EGRIVLIGTT APGLLDLRST PVNPAYPGVE
VHANVISGML DSIYKLRPEY SQGLLFITVL AVGFVLSVMM PILSATWSLL VALAVLVASV
AINSVLYFQA GLVLPVAVVL LLVLAIFMFD VAYGYLAESR SKRQMVDLFG EYVAPELVSE
MASDPTRYSM EGESRELTVL FSDVRGFTTI SESLQPNELR EYINEYLTVM SEIIRSHRGT
LDKYIGDAIM AFWGAPIADA EHAELATKAA IAMQEEAVRL NERLLARNWP TLAIGVGVNT
GQMRVGDMGS KIRRAYTVMG DAVNLGSRLE GITKTYGVGV IVGPQTKAAV PGMVFQELDA
VKVKGKNEPV SIYAPLGERT VLTQASLDQL EQWNRFLKAF RAQQWLPARE QLAGLQGSLV
TNPTLHALYE NRIAYFELNP PPDNWDGVTQ FDTK
//
