ID A6GY63_FLAPJ Unreviewed; 635 AA.
AC A6GY63;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN Name=acsA {ECO:0000313|EMBL:CAL43036.1};
GN OrderedLocusNames=FP0942 {ECO:0000313|EMBL:CAL43036.1};
OS Flavobacterium psychrophilum (strain ATCC 49511 / DSM 21280 / CIP 103535 /
OS JIP02/86).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=402612 {ECO:0000313|EMBL:CAL43036.1, ECO:0000313|Proteomes:UP000006394};
RN [1] {ECO:0000313|EMBL:CAL43036.1, ECO:0000313|Proteomes:UP000006394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49511 / DSM 21280 / CIP 103535 / JIP02/86
RC {ECO:0000313|Proteomes:UP000006394};
RX PubMed=17592475; DOI=10.1038/nbt1313;
RA Duchaud E., Boussaha M., Loux V., Bernardet J.F., Michel C., Kerouault B.,
RA Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P., Gibrat J.F.,
RA Claverol S., Dumetz F., Le Henaff M., Benmansour A.;
RT "Complete genome sequence of the fish pathogen Flavobacterium
RT psychrophilum.";
RL Nat. Biotechnol. 25:763-769(2007).
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DR EMBL; AM398681; CAL43036.1; -; Genomic_DNA.
DR RefSeq; WP_011963090.1; NC_009613.3.
DR RefSeq; YP_001295850.1; NC_009613.3.
DR AlphaFoldDB; A6GY63; -.
DR STRING; 402612.FP0942; -.
DR EnsemblBacteria; CAL43036; CAL43036; FP0942.
DR GeneID; 66552340; -.
DR KEGG; fps:FP0942; -.
DR PATRIC; fig|402612.5.peg.953; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_3_6_10; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000006394; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:CAL43036.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006394}.
FT DOMAIN 12..68
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 70..462
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 519..598
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 635 AA; 71718 MW; D577DD47F0F9AB6E CRC64;
MSYYKIDNLE QYFKHYNKSI REPRKFWGKI ASENFTWYQE CEKVVEFDMV EAKIEWFKGA
KVNIVKNCID RHLARRGEKT AIIFEPNNPN EEALHISYNE LYVRVSKMAN VLREQGIEKG
DRVCIYLPMI PELAIATLAC ARIGAIHSVV FAGFSESAVA SRINDSECKM VITSDGGFRG
EKTIDLKAII DEALEKCPCV TKVLVVKRTN TSVKMKEGRD IWLQPLLDEA LDNNMPEIMD
AEDPLFILYT SGSTGKPKGM VHTTAGYMVY SAYTFKNVFN YEDDDIFWCT ADIGWITGHS
YILYGPLLNG ATTVIFEGVP SYPDFSRFWE VIEKHKVTQF YTAPTAIRAL AKENLSYVQK
YPLKSLKVIG SVGEPINEEA WHWYNDHVGG KRCPMVDTWW QTETGGIMIS PIAFVTPTKP
TYASLPLPGI QPILMNEKRN EIEENQVSGS LCIKFPWPGI ARTIWGNHQR YKETYFSAFP
GKYFTGDGAL RDEVGYYRIT GRVDDVVIVS GHNLGTAPIE DAINEHPAVA ESAIVGFPHD
LKGNALYGFV MLKESGETRD KTNLAKEINQ NVSDHIGPIA KLDKIQFVSG LPKTRSGKIM
RRILRKIAEG DFANFGDITT LLNPEIVEEI KEGKL
//
