ID A6LAW8_PARD8 Unreviewed; 399 AA.
AC A6LAW8;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Precorrin-6Y C5,15-methyltransferase, decarboxylating {ECO:0000313|EMBL:ABR42832.1};
GN OrderedLocusNames=BDI_1066 {ECO:0000313|EMBL:ABR42832.1};
OS Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM
OS 5825 / NCTC 11152).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC Parabacteroides.
OX NCBI_TaxID=435591 {ECO:0000313|EMBL:ABR42832.1, ECO:0000313|Proteomes:UP000000566};
RN [1] {ECO:0000313|EMBL:ABR42832.1, ECO:0000313|Proteomes:UP000000566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152
RC {ECO:0000313|Proteomes:UP000000566};
RX PubMed=17579514; DOI=10.1371/journal.pbio.0050156;
RA Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C.,
RA Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H.,
RA Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K.,
RA Knight R.D., Gordon J.I.;
RT "Evolution of symbiotic bacteria in the distal human intestine.";
RL PLoS Biol. 5:1574-1586(2007).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
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DR EMBL; CP000140; ABR42832.1; -; Genomic_DNA.
DR RefSeq; WP_011966305.1; NC_009615.1.
DR AlphaFoldDB; A6LAW8; -.
DR STRING; 435591.BDI_1066; -.
DR PaxDb; 435591-BDI_1066; -.
DR KEGG; pdi:BDI_1066; -.
DR PATRIC; fig|435591.13.peg.1055; -.
DR eggNOG; COG2241; Bacteria.
DR eggNOG; COG2242; Bacteria.
DR HOGENOM; CLU_031955_1_1_10; -.
DR BioCyc; PDIS435591:G1G5A-1102-MONOMER; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000000566; Chromosome.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11644; Precorrin-6Y-MT; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR012818; CbiE.
DR InterPro; IPR006365; Cbl_synth_CobL.
DR InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR02467; CbiE; 1.
DR NCBIfam; TIGR02469; CbiT; 1.
DR PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR PIRSF; PIRSF036428; CobL; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ABR42832.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000566};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABR42832.1}.
FT DOMAIN 4..190
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 399 AA; 45673 MW; 4C757F772A324763 CRC64;
MNRFYVIGLD DNMRQYFPPE ILEIISSHRV FSGGVRHHEI VRSLLPEKAD WIDIKVPLDE
VFDRYRSYDG RESIVVFASG DPLFFGFAVT IQNRLPDAQI RLYPSFNSLQ LLAQNLLMPY
HDMRIVSLTG RPWHEFDRAL IESASKIGVL TDREHTPTTI ARRMLEYGYD NYTMFVGERL
GNTERQSIRQ FSIQAAAMNN FVHPNCLILK KERDGHSRKF GLPDSAFEHL NGREKMITKM
PIRLLSLSML DLRNRERFWD IGFCTGSVSI EAKLLFPHLH ITSFEIREEG RKLMTENCRR
FGTPGIEAII GDFLSVDLSA LEAPDAIFIG GHGGKLVEIL MVVSKKMKEN GVIVFNSVSD
ESKALLEEAV RQTGLRISAQ TRITIDDFNT ITVNVIYKL
//
