ID A6LZ59_CLOB8 Unreviewed; 867 AA.
AC A6LZ59;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Pyruvate phosphate dikinase, PEP/pyruvate-binding {ECO:0000313|EMBL:ABR35639.1};
GN OrderedLocusNames=Cbei_3516 {ECO:0000313|EMBL:ABR35639.1};
OS Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium
OS acetobutylicum).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=290402 {ECO:0000313|EMBL:ABR35639.1, ECO:0000313|Proteomes:UP000000565};
RN [1] {ECO:0000313|EMBL:ABR35639.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Sims D., Brettin T., Bruce D., Tapia R., Brainard J., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Bennet G.,
RA Cann I., Chen J.-S., Contreras A.L., Jones D., Kashket E., Mitchell W.,
RA Stoddard S., Schwarz W., Qureshi N., Young M., Shi Z., Ezeji T., White B.,
RA Blaschek H., Richardson P.;
RT "Complete sequence of Clostridium beijerinckii NCIMB 8052.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABR35639.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RX PubMed=21962126; DOI=10.1186/1471-2164-12-479;
RA Wang Y., Li X., Mao Y., Blaschek H.P.;
RT "Single-nucleotide resolution analysis of the transcriptome structure of
RT Clostridium beijerinckii NCIMB 8052 using RNA-Seq.";
RL BMC Genomics 12:479-479(2011).
RN [3] {ECO:0000313|EMBL:ABR35639.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RX PubMed=22433311; DOI=10.1186/1471-2164-13-102;
RA Wang Y., Li X., Mao Y., Blaschek H.P.;
RT "Genome-wide dynamic transcriptional profiling in clostridium beijerinckii
RT NCIMB 8052 using single-nucleotide resolution RNA-Seq.";
RL BMC Genomics 13:102-102(2012).
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DR EMBL; CP000721; ABR35639.1; -; Genomic_DNA.
DR RefSeq; WP_012059689.1; NC_009617.1.
DR AlphaFoldDB; A6LZ59; -.
DR KEGG; cbe:Cbei_3516; -.
DR eggNOG; COG0574; Bacteria.
DR eggNOG; COG3848; Bacteria.
DR HOGENOM; CLU_005950_0_0_9; -.
DR Proteomes; UP000000565; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.50.30.10; Phosphohistidine domain; 1.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR008279; PEP-util_enz_mobile_dom.
DR InterPro; IPR036637; Phosphohistidine_dom_sf.
DR InterPro; IPR002192; PPDK_AMP/ATP-bd.
DR PANTHER; PTHR43615; PHOSPHOENOLPYRUVATE SYNTHASE-RELATED; 1.
DR PANTHER; PTHR43615:SF1; PHOSPHOENOLPYRUVATE SYNTHASE-RELATED; 1.
DR Pfam; PF00391; PEP-utilizers; 1.
DR Pfam; PF01326; PPDK_N; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52009; Phosphohistidine domain; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ABR35639.1};
KW Pyruvate {ECO:0000313|EMBL:ABR35639.1};
KW Transferase {ECO:0000313|EMBL:ABR35639.1}.
FT DOMAIN 17..315
FT /note="Pyruvate phosphate dikinase AMP/ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF01326"
FT DOMAIN 791..862
FT /note="PEP-utilising enzyme mobile"
FT /evidence="ECO:0000259|Pfam:PF00391"
SQ SEQUENCE 867 AA; 97756 MW; 3F4653FA6FECC499 CRC64;
MNSYVLSFQE IDKTKISMVG GKGANLGELS RITEILVPEG FCVTTEAYKK ITENNEELKG
LLDELSHFGV EDIEKIREIS SEIRKVIEGI TIPEVISEEI ARFILRFGEK DSYAVRSSAT
AEDLPTASFA GQQDTYLNII GKESILKHIR KCLASLFTER AVIYRIQNGF NHNKVHLSVV
VQRMVFPKAA GILFTADPVT CNRKVVSIDA SFGLGEALVS GLVNADNYRV RNDKIVDKKI
STKKLGIYSL KDGGTEKLAI EPEMQNSQVL TDEQILRLAH MGRKIEEHFG CPQDIEWCLA
HDTFYIVQSR PITTLYPIPE VNDEGKHVYL SVGHQQMMTD PLKPLGMSLK ELISFGRWFK
AGGRLFVDVA PMLASPDGRK NLLNNMKQLE PLTEDAIMTI IERDFIKCLP NDKEKKSDIK
SKSAAGSETQ KELDPTIVSE LIKKSQSSIE ELKQKIQTKS GVDLIDFILE DINELKRILF
DPQSTAVFMS AINASLWINE KMNKWLGEKN AADTLSQSVP NNITSEMGLE LMDVADVIRP
YPEIVDFLQN AKDDNFLEEV IKFHGGKETR DAILAYLRKF GMRCSGEIDI TRTRFSEKPI
TLVPMILSNI KNFEPNAGKK KFEQGRQEAL NKEQELLSRL RELPDGEEKA KETKRNIDLI
RNFIGYREYP KYGMISRYFV YKQALMKEAE RLVQDGVIHE KEDIYYLNLE ELREVVHTNK
LDYDIIMKRK EEHKLNEKLT PPRVMTSDGE IIIGKYKREN IPAGAIQGLP VSSGVIEGRA
RVILNMEDAV LEAGDILVTA FTDPSWTPLF VSIKGLVTEI GGLMTHGAVI AREYGLPAVV
GVENATKLIK DGQRIRVNGT EGYIEIL
//
