ID A6Q0H4_9BURK Unreviewed; 333 AA.
AC A6Q0H4;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=Protein RecA {ECO:0000256|ARBA:ARBA00015553, ECO:0000256|RuleBase:RU000526};
DE AltName: Full=Recombinase A {ECO:0000256|RuleBase:RU000526};
DE Flags: Fragment;
GN Name=recA {ECO:0000313|EMBL:CAO01515.1};
OS Burkholderia diffusa.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=488732 {ECO:0000313|EMBL:CAO01515.1};
RN [1] {ECO:0000313|EMBL:CAO01515.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LMG 24065T {ECO:0000313|EMBL:CAO01515.1};
RA Vanlaere E., Lipuma J.J., Baldwin A., Henry D., De Brandt E.,
RA Mahenthiralingam E., Speert D., Dowson C., Vandamme P.;
RT "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia
RT arboris sp. nov., Burkholderia seminalis sp. nov. and Burkholderia
RT metallica sp. nov., novel species within the Burkholderia cepacia
RT complex.";
RL Int. J. Syst. Evol. Microbiol. 58:1580-1590(2008).
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. It interacts with LexA causing its activation and leading to its
CC autocatalytic cleavage. {ECO:0000256|ARBA:ARBA00025580}.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000256|ARBA:ARBA00009391,
CC ECO:0000256|RuleBase:RU004527}.
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DR EMBL; AM748103; CAO01515.1; -; Genomic_DNA.
DR AlphaFoldDB; A6Q0H4; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd00983; RecA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00268; RecA; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049261; RecA-like_C.
DR InterPro; IPR049428; RecA-like_N.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR023400; RecA_C_sf.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR NCBIfam; TIGR02012; tigrfam_recA; 1.
DR PANTHER; PTHR45900:SF1; MITOCHONDRIAL DNA REPAIR PROTEIN RECA HOMOLOG-RELATED; 1.
DR PANTHER; PTHR45900; RECA; 1.
DR Pfam; PF00154; RecA; 1.
DR Pfam; PF21096; RecA_C; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54752; RecA protein, C-terminal domain; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004527};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU004527};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172,
KW ECO:0000256|RuleBase:RU004527};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU000526};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004527};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004527};
KW SOS response {ECO:0000256|RuleBase:RU000526}.
FT DOMAIN 28..187
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 192..265
FT /note="RecA family profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50163"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAO01515.1"
FT NON_TER 333
FT /evidence="ECO:0000313|EMBL:CAO01515.1"
SQ SEQUENCE 333 AA; 35733 MW; D7702D0B4ECD8EC4 CRC64;
LAAALAQIDK QFGKGSIMRM GDGEAAEDIQ VVSTGSLGLD IALGVGGLPR GRVVEIYGPE
SSGKTTLTLQ VIAELQKLGG TAAFIDAEHA LDVQYAAKLG VNVPELLISQ PDTGEQALEI
TDALVRSGSI DMIVIDSVAA LVPKAEIEGE MGDSLPGLQA RLMSQALRKL TGTIKRTNCL
VIFINQIRMK IGVMFGNPET TTGGNALKFY SSVRLDIRRI GSIKKNDEVI GNETRVKVVK
NKVSPPFREA IFDILYGEGI SRQGEIIDLG VQAKIVDKAG AWYSYNGEKI GQGKDNAREF
LRENPEIARE IENRIRESLG VAAMPDGARV ARS
//
