ID A6Q0S3_WEICO Unreviewed; 128 AA.
AC A6Q0S3;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 24-JAN-2024, entry version 70.
DE RecName: Full=phenylalanine--tRNA ligase {ECO:0000256|ARBA:ARBA00012814};
DE EC=6.1.1.20 {ECO:0000256|ARBA:ARBA00012814};
DE Flags: Fragment;
GN Name=pheS {ECO:0000313|EMBL:CAO78553.1};
GN Synonyms=PheS {ECO:0000313|EMBL:CAO00642.1};
OS Weissella confusa (Lactobacillus confusus).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae; Weissella.
OX NCBI_TaxID=1583 {ECO:0000313|EMBL:CAO78553.1};
RN [1] {ECO:0000313|EMBL:CAO00642.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=R-27963 {ECO:0000313|EMBL:CAO00642.1}, and R-27966
RC {ECO:0000313|EMBL:CAO00644.1};
RX PubMed=17675431; DOI=10.1128/AEM.00894-07;
RA Scheirlinck I., Van Der Meulen R., Van Schoor A., Vancanneyt M.,
RA De Vuyst L., Vandamme P., Huys G.;
RT "Influence of geographical origin and flour type on diversity of lactic
RT acid bacteria in traditional Belgian sourdoughs.";
RL Appl. Environ. Microbiol. 73:6262-6269(2007).
RN [2] {ECO:0000313|EMBL:CAO78553.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain: LMG 9497 {ECO:0000313|EMBL:CAO78553.1};
RA De Bruyne K., Vancanneyt M., Franz C., Schillinger U., Mozzi F.,
RA Font de Valdez G., De Vuyst L., Vandamme P.;
RT "Pediococcus argentinum sp. nov. from Argentinean wheat flour.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:CAO78553.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=R-27963 {ECO:0000313|EMBL:CAO00642.1}, R-27966
RC {ECO:0000313|EMBL:CAO00644.1}, R-34334 {ECO:0000313|EMBL:CAP16239.1},
RC and Type strain: LMG 9497 {ECO:0000313|EMBL:CAO78553.1};
RA Scheirlinck I.P.D.;
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CAP16239.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=R-34334 {ECO:0000313|EMBL:CAP16239.1};
RX PubMed=18310426; DOI=10.1128/AEM.02771-07;
RA Scheirlinck I., Van der Meulen R., Van Schoor A., Vancanneyt M.,
RA De Vuyst L., Vandamme P., Huys G.;
RT "Taxonomic structure and stability of the bacterial community in Belgian
RT sourdough ecosystems assessed by culturing and population fingerprinting.";
RL Appl. Environ. Microbiol. 74:2414-2423(2008).
RN [5] {ECO:0000313|EMBL:CAR40217.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain: LMG 9497 {ECO:0000313|EMBL:CAR40217.1};
RX PubMed=19801391; DOI=10.1099/ijs.0.019323-0;
RA De Bruyne K., Camu N., De Vuyst L., Vandamme P.;
RT "Weissella fabaria sp. nov., from a Ghanaian cocoa fermentation.";
RL Int. J. Syst. Evol. Microbiol. 60:1999-2005(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) +
CC L-phenylalanyl-tRNA(Phe); Xref=Rhea:RHEA:19413, Rhea:RHEA-COMP:9668,
CC Rhea:RHEA-COMP:9699, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:58095, ChEBI:CHEBI:78442,
CC ChEBI:CHEBI:78531, ChEBI:CHEBI:456215; EC=6.1.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00000395};
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DR EMBL; AM745647; CAO00642.1; -; Genomic_DNA.
DR EMBL; AM745649; CAO00644.1; -; Genomic_DNA.
DR EMBL; AM749816; CAO78553.1; -; Genomic_DNA.
DR EMBL; AM901526; CAP16239.1; -; Genomic_DNA.
DR EMBL; FM202105; CAR40217.1; -; Genomic_DNA.
DR AlphaFoldDB; A6Q0S3; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016740; F:transferase activity; IEA:UniProt.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0043039; P:tRNA aminoacylation; IEA:InterPro.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002319; Phenylalanyl-tRNA_Synthase.
DR PANTHER; PTHR11538:SF41; PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11538; PHENYLALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF01409; tRNA-synt_2d; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000313|EMBL:CAR40217.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Ligase {ECO:0000313|EMBL:CAR40217.1}.
FT DOMAIN 8..108
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAO78553.1"
FT NON_TER 128
FT /evidence="ECO:0000313|EMBL:CAO78553.1"
SQ SEQUENCE 128 AA; 14653 MW; EF0400A4F46CF840 CRC64;
DTFYITPEIL MRTQTSPVQA RTLESHDFNA GPLKMVSPGR VYRRDTDDAT HSHQFHQMEG
LVIDKHITMG DLKGTLLAVA RKLFGEDHEI RLRPSYFPFT EPSVEVDVSW NAVTPDMAPE
DIEWIEVL
//
