ID A6Q4E6_NITSB Unreviewed; 581 AA.
AC A6Q4E6;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Sugar epimerase/dehydratase {ECO:0000313|EMBL:BAF70355.1};
GN OrderedLocusNames=NIS_1247 {ECO:0000313|EMBL:BAF70355.1};
OS Nitratiruptor sp. (strain SB155-2).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Nautiliales;
OC Nitratiruptoraceae; Nitratiruptor.
OX NCBI_TaxID=387092 {ECO:0000313|EMBL:BAF70355.1, ECO:0000313|Proteomes:UP000001118};
RN [1] {ECO:0000313|EMBL:BAF70355.1, ECO:0000313|Proteomes:UP000001118}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB155-2 {ECO:0000313|EMBL:BAF70355.1,
RC ECO:0000313|Proteomes:UP000001118};
RX PubMed=17615243; DOI=10.1073/pnas.0700687104;
RA Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K.,
RA Horikoshi K.;
RT "Deep-sea vent epsilon-proteobacterial genomes provide insights into
RT emergence of pathogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
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DR EMBL; AP009178; BAF70355.1; -; Genomic_DNA.
DR AlphaFoldDB; A6Q4E6; -.
DR STRING; 387092.NIS_1247; -.
DR KEGG; nis:NIS_1247; -.
DR eggNOG; COG1086; Bacteria.
DR HOGENOM; CLU_013560_5_2_7; -.
DR InParanoid; A6Q4E6; -.
DR Proteomes; UP000001118; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001118};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 268..541
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 581 AA; 67067 MW; E3F49BAAFDF261EA CRC64;
MKLSNFLKPT NMKRAFFFLL GDIVISFLTL YLAYLLRFNF SIPKEYLYNF FNIALVLILF
KIFFYYLFKL YFVSWRFFSL QELKSLLMAT TLAYFLGGAT LLLLRDIFSP FPRSVIFIDY
FLSILFIGFF RISKRLMYEK ISMNRTPAFI FGANDKAISL LKQDIPYSII KIYDNEKNIV
GTYMYGYKVY DIKNVDNKIK TAIITKELSQ KDLDKLVDFL HGQGIVNVKI YNPFEERIKD
ISIEDILARK PKDLDKNAIR AFVKNKKILI TGAGGSIGSE IARQCEKYGA KKLVLVDNCE
YNLYVINEEL HLPRKPYLIN IVDKDALEEV FEKEEPQIVI HAAAYKHVPI CEYNPRSAVI
NNILGSKNVI DLSIKRRVQD FIFISTDKAV RPTNIMGATK RVCELYVQNV DSKNTKMCTV
RFGNVLGSSG SVVPKFKKLI SQNKPLPVTH PEVTRYFMLI PEACQLVLQA GSLAKTGETF
ILDMGEPVKI VDLAKKMLKL SGKDDNAIVF TGLRPGEKLY EELLFNEASK KTKYKDIFVA
ESTNYSIDKL QYQIEYLLKC EKKEDIIKTL REIVPEYNPK R
//
