ID A6Q9I8_SULNB Unreviewed; 1223 AA.
AC A6Q9I8;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=SUN_1192 {ECO:0000313|EMBL:BAF72147.1};
OS Sulfurovum sp. (strain NBC37-1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Sulfurovaceae; Sulfurovum.
OX NCBI_TaxID=387093 {ECO:0000313|EMBL:BAF72147.1, ECO:0000313|Proteomes:UP000006378};
RN [1] {ECO:0000313|EMBL:BAF72147.1, ECO:0000313|Proteomes:UP000006378}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBC37-1 {ECO:0000313|EMBL:BAF72147.1,
RC ECO:0000313|Proteomes:UP000006378};
RX PubMed=17615243; DOI=10.1073/pnas.0700687104;
RA Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K.,
RA Horikoshi K.;
RT "Deep-sea vent epsilon-proteobacterial genomes provide insights into
RT emergence of pathogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007).
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DR EMBL; AP009179; BAF72147.1; -; Genomic_DNA.
DR RefSeq; WP_011980880.1; NC_009663.1.
DR AlphaFoldDB; A6Q9I8; -.
DR STRING; 387093.SUN_1192; -.
DR KEGG; sun:SUN_1192; -.
DR eggNOG; COG3287; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR eggNOG; COG5002; Bacteria.
DR HOGENOM; CLU_268425_0_0_7; -.
DR OrthoDB; 9790732at2; -.
DR Proteomes; UP000006378; Chromosome.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR019494; FIST_C.
DR InterPro; IPR013702; FIST_domain_N.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF08495; FIST; 1.
DR Pfam; PF10442; FIST_C; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00897; FIST; 1.
DR SMART; SM01204; FIST_C; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 497..549
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 546..589
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 666..720
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 738..790
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 829..962
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 971..1223
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 396..423
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1223 AA; 140207 MW; ED0276EAEDE5D03E CRC64;
MRTVNTYYTD KQHFQEFVLQ VDIADNDQLL IQVFTSYTDK TKIEVMTNEI TSLFPRAVII
GATTDGEICS GKVTTHTHVI SLTQFEDTVL YPVCVDADGK MDSHETGQTL AEAVTSQEDK
KVLIAFLDGT KSNGEEFLRG IDAVCPELTV AGGMAGDYAE FKNTYVFTGE QIISRGAVGV
ALSNPKLHIY TKYNFNWKPI GRSLVVTKVD RNRVYTIDDM SAYDVYKKYF GEEVAQKLPA
IGIEFPLIIK KGGDLTARAI LSVHEDGSLS FSGNFHQGDT VYFGYGDAKM LLDQSEQIGQ
DIVSQPVECI FIYSCMARRR FLPELIEQET KPLQSVAPVS GFFTYGEFFS FSGKKALLNQ
TMTILGLSES SHKTDKKIVK QKIVLNEYQA SAKALSHFIN VNMQEAQKEF QKLEEKTRVI
EAQKEALHRI QQIGHFGSWE IDLKHNTAQW SKRSYDIYQL DPENTQPTLD TFLSRVVKKD
RHIAYEGLRS LQDGKVKSVS LRVRREDGEI ITVLINAKML FDKQGEPDRI VGTTLDITEQ
LRLKQENKEL GDIIEYASGE VLIVELGTFR YLYANDAAIR KLGYTREEIC RLSILDINRE
ITHKQLREFE KEIRANGTVL NRTVYTKKDD SKYPVQTYAQ YGKYHNRDAM IIFNLDISHL
VAIEKKEIEQ AQILEQIHDA VISTDLDNKI IHWNHGATEL LGYDASEMIG RNIDILYPED
ELKKAQWMKM QTLLYGSYRD QIRKQTKEGK MIYTDVSASV LRDEKKRIIG ITRYSQDISQ
KKEIELELLE QTKQLNFQAY HDPLTQLPNR TLFNDRLEQT ITYAHRHNEK FGVFFIDLDN
FKLINDTLGH HLGDEVLKIV SHRFSKCIRE EDTLSRLGGD EFTVLVHELN TPESAAKIAG
KMMGSLKEEV VVEGQTLHVT ASIGISLYPR DAVYKNDLLK YADSAMYKAK EVGRNNYQFY
SSEMTNLAME KATMEKELRK AIAKNQLRVY YQPQINARNR SVVGLEALVR WEHPEKGLIL
PDAFIPLAEE TGLIREMDYY VMHQAMSDMV EWYHIGLNPG ILSLNLPISQ LMKENFFYTL
QNTILKTGFK VKWLTFEITE TQVMLNPKHS IKKLYMLNQM GIKISIDDFG TGYSSLAYLK
RLPVDKLKID KTFIFDLPYN TEDCAITNAV IALAESLHLE IIAEGVEHRD QVRYLLENGC
YIIQGYHYSR PIPKQEMTQY LMR
//
