ID A6QPI9_BOVIN Unreviewed; 271 AA.
AC A6QPI9; F1MXH2;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=TPSB1 protein {ECO:0000313|EMBL:AAI49343.1};
GN Name=TPSB1 {ECO:0000313|EMBL:AAI49343.1};
GN Synonyms=LOC786948 {ECO:0000313|Ensembl:ENSBTAP00000009636.5};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAI49343.1};
RN [1] {ECO:0000313|EMBL:AAI49343.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hereford {ECO:0000313|EMBL:AAI49343.1};
RC TISSUE=Fetal spinal column {ECO:0000313|EMBL:AAI49343.1};
RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y.,
RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C.,
RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J.,
RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J.,
RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., Siddiqui A.,
RA Holt R., Jones S.J., Marra M.A.;
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000009636.5, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000009636.5,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSBTAP00000009636.5}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000009636.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BC149342; AAI49343.1; -; mRNA.
DR RefSeq; NP_001306823.1; NM_001319894.1.
DR STRING; 9913.ENSBTAP00000009636; -.
DR MEROPS; S01.118; -.
DR PaxDb; 9913-ENSBTAP00000009636; -.
DR Ensembl; ENSBTAT00000009636.6; ENSBTAP00000009636.5; ENSBTAG00000016520.6.
DR GeneID; 786948; -.
DR KEGG; bta:786948; -.
DR VEuPathDB; HostDB:ENSBTAG00000016520; -.
DR eggNOG; KOG3627; Eukaryota.
DR GeneTree; ENSGT00940000162207; -.
DR HOGENOM; CLU_006842_13_1_1; -.
DR OMA; NQLCDAE; -.
DR OrthoDB; 4629979at2759; -.
DR TreeFam; TF351676; -.
DR Reactome; R-BTA-1592389; Activation of Matrix Metalloproteinases.
DR Proteomes; UP000009136; Chromosome 25.
DR Bgee; ENSBTAG00000016520; Expressed in aorta and 92 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR PANTHER; PTHR24253; TRANSMEMBRANE PROTEASE SERINE; 1.
DR PANTHER; PTHR24253:SF32; TRYPTASE; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..271
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014083965"
FT DOMAIN 27..268
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 271 AA; 30000 MW; 011AE6098B6D1796 CRC64;
MLHLLALALL LSLVSAAPGQ ALQRAGIVGG QEAPGSRWPW QVSLRVSRRY WRHHCGGSLI
HPQWVLTAAH CVGPEVHGPS YFRVQLREQH LYYQDQLLPI SRIIPHPNYY SVKNGADIAL
LELDKLVNIS WHVQPVTLPP ESETFPPGTQ CWVTGWGNVD NGRRLPPPFP LKQVKVPVVE
NSVCDRKYHS GLSTGDNVPI VREDMLCAGD SGRNFCQGDS GGPLVCKVNG TWLQAGVVSW
GDGCAKPNRP GIYTRVTSYL DWIHQYVPQG P
//
