ID A6QPT8_BOVIN Unreviewed; 537 AA.
AC A6QPT8;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=BTNL9 protein {ECO:0000313|EMBL:AAI49480.1};
DE SubName: Full=Butyrophilin like 9 {ECO:0000313|Ensembl:ENSBTAP00000067995.1};
GN Name=BTNL9 {ECO:0000313|EMBL:AAI49480.1,
GN ECO:0000313|Ensembl:ENSBTAP00000067995.1,
GN ECO:0000313|VGNC:VGNC:109404};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAI49480.1};
RN [1] {ECO:0000313|EMBL:AAI49480.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hereford {ECO:0000313|EMBL:AAI49480.1};
RC TISSUE=Thymus {ECO:0000313|EMBL:AAI49480.1};
RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y.,
RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C.,
RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J.,
RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J.,
RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., Siddiqui A.,
RA Holt R., Jones S.J., Marra M.A.;
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000067995.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000067995.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSBTAP00000067995.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000067995.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. BTN/MOG family.
CC {ECO:0000256|ARBA:ARBA00007591}.
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DR EMBL; BC149479; AAI49480.1; -; mRNA.
DR RefSeq; NP_001096815.1; NM_001103345.1.
DR STRING; 9913.ENSBTAP00000067995; -.
DR PaxDb; 9913-ENSBTAP00000055913; -.
DR Ensembl; ENSBTAT00000069332.1; ENSBTAP00000067995.1; ENSBTAG00000047420.2.
DR Ensembl; ENSBTAT00000074652.1; ENSBTAP00000071716.1; ENSBTAG00000047420.2.
DR GeneID; 100125313; -.
DR KEGG; bta:100125313; -.
DR CTD; 153579; -.
DR VEuPathDB; HostDB:ENSBTAG00000047420; -.
DR VGNC; VGNC:109404; BTNL9.
DR GeneTree; ENSGT00940000160338; -.
DR HOGENOM; CLU_013137_7_4_1; -.
DR OMA; WEVHVGC; -.
DR OrthoDB; 2943983at2759; -.
DR Reactome; R-BTA-8851680; Butyrophilin (BTN) family interactions.
DR Proteomes; UP000009136; Chromosome 7.
DR Bgee; ENSBTAG00000047420; Expressed in bone marrow and 103 other cell types or tissues.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0005102; F:signaling receptor binding; IBA:GO_Central.
DR GO; GO:0001817; P:regulation of cytokine production; IBA:GO_Central.
DR GO; GO:0050852; P:T cell receptor signaling pathway; IBA:GO_Central.
DR CDD; cd05713; IgV_MOG_like; 1.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF141; BUTYROPHILIN-LIKE PROTEIN 9; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00409; IG; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..537
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041156475"
FT TRANSMEM 259..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..150
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 158..244
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 315..512
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 338..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 286..313
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 350..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 61002 MW; A2411FBBC410529B CRC64;
MDFSVFLNSY QRGRLPSSLF FLTHLLLLLQ PRVLCSEEIR VVGHEEPILA HVGDEVEFSC
HLSPYRDAQH MEILWFWSQA SNVVHLYREQ QEFYGWQMKQ FQNRTQLIRD DIIDGSVTLR
LHLVVPADQG LYGCRFLSSD FTGEATWELE VAGLGSDPHI SIEGFKEGGI QLRCHSNGWY
PKPQAQWRDR HGRCLPPETE NITEDVQGLF SLETSVVVQE GAHSNVSCSI QNHLLGQKKE
FVVHIADVFL PGTSPWKRAF LGTLVGLPLL LALLMMLVLY FFRKQRKSQE KLKKQAERDK
GKLTVELGKL QVELDWRRAE GQAEWRAAQR HAVDVTLDPG SAHPSLEVSE DGKSVSSLRT
APGSENPQWL SEQTCVLSRE LFSTGRHYWE VHVGRRSRWF LGVCLAAVPR AGHARMSPAT
GYWVMGLWNS CEYFVLDQHR VPLSVRVPPR CVGIFLDIEA GKLSFFNVSD GSHIFTFTDT
FPGMLCAYFR PRAHDGSEHP DPLTICPLPV GEKHVLEEED SDAWLQPYES SNTDLGL
//
