ID   A6QST8_AJECN            Unreviewed;       463 AA.
AC   A6QST8;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=Methyltransferase domain-containing protein {ECO:0000259|Pfam:PF13679};
GN   ORFNames=HCAG_00444 {ECO:0000313|EMBL:EDN02580.1};
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN02580.1, ECO:0000313|Proteomes:UP000009297};
RN   [1] {ECO:0000313|Proteomes:UP000009297}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
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DR   EMBL; CH476655; EDN02580.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6QST8; -.
DR   STRING; 339724.A6QST8; -.
DR   VEuPathDB; FungiDB:HCAG_00444; -.
DR   HOGENOM; CLU_016581_1_0_1; -.
DR   OMA; LQAPYNW; -.
DR   OrthoDB; 3060170at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   PANTHER; PTHR12496; CGI-41 METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR12496:SF0; METHYLTRANFER_DOM DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13679; Methyltransf_32; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT   DOMAIN          11..234
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13679"
FT   REGION          80..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          157..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        167..189
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   463 AA;  50614 MW;  D53E89B1CA229232 CRC64;
     MEAGGAEVIS HIVDFGSGQN YLGRTLASPL YNRQIIAIER RQNNISGAMG KDVLAKLKKN
     KTKMKNQGKK ENASGVVEVA AESDSAVSTS RNGEEVRVED GKEDVIDLDM GGCVGRNNGR
     TTYNAVAKEK HGSKGSMDYI EHDIQNGYLE AIVRHVVEPS SPPSPNGQNP QSQRTCKYPN
     SPPSSESNTK PARVMVISLH SCGNLVHHGI RSLILNPSVT AIAMIGCCYN LMTERLGPAT
     YKLPILRSLH PRLEATSNAY DPHGFPMSKK LETYRHEGGT GIKLNITARM MAVQAPYNWG
     PKDSEIFFTR HFYRALLQRV LVDYGVVPVP GIGGPIGDVP LEGGGKAEEV ASGTPLIVGS
     MRKAAFVSFA AYAHAAIEKL SRDAHYGGAI REKRYEARYA VYRKNLSIVW SLMAFSAGVV
     ESVIVADRWL FLREQAEVKE AWVEAVFDYQ QSPRNLVVVG IKG
//