ID   A6QWQ4_AJECN            Unreviewed;       520 AA.
AC   A6QWQ4;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   ORFNames=HCAG_01811 {ECO:0000313|EMBL:EDN03946.1};
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN03946.1, ECO:0000313|Proteomes:UP000009297};
RN   [1] {ECO:0000313|Proteomes:UP000009297}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
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DR   EMBL; CH476655; EDN03946.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6QWQ4; -.
DR   STRING; 339724.A6QWQ4; -.
DR   VEuPathDB; FungiDB:HCAG_01811; -.
DR   HOGENOM; CLU_000680_25_2_1; -.
DR   OMA; YELNCEA; -.
DR   OrthoDB; 2202746at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR33481; REVERSE TRANSCRIPTASE; 1.
DR   PANTHER; PTHR33481:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT   DOMAIN          1..159
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   520 AA;  59383 MW;  EF21510812CD3F63 CRC64;
     MTGAYDKVLR ERMVHILRRL GIPRDLVGWV ASFMTNRKST IAFEGQESDT FDIPAGIPQG
     SPLSPILFLF YNEELVRICS RPGRPVVCIA FVDDVNVMAY GQSTEDNCRE LLRMHRACEE
     WAARHGAVFA PQKYELMHFT RARNQFNLQA ELRLPGQTIQ PKQVMRVLGV WLDSRLRRKG
     HLDAVAGKMK TQVRALSQTT QSTWGLPLRQ ARMVYNMVIR PALTYGAIAW HQPQGQGGTG
     PAKSGLALKL TTVQNSCLRI VAGAYKRTPT STLEAETHTV PLDIHLDGLV AKAVNRMKAS
     GMAQQIENAC AAIRTRLRHR GVTRGAQRHM GAVVHPAALP VDWEQQWIQG AKERATAEMT
     PEQRANLDQA SYNHWLKREQ LWRWVQRWKR REPPWGERHG RPPDKKILKW HTGLRKARST
     IIIQLRSGKT GLAAFLNRCK VPEFPTPRCP CGYEWETVEH VLIHCGRWEQ QRQGLIRNGR
     LDKRMLLDTK EGLHLLSNWW MESGILGQFT LARELTHYVP
//