ID A6QYK4_AJECN Unreviewed; 668 AA.
AC A6QYK4;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Transglutaminase-like domain-containing protein {ECO:0000259|SMART:SM00460};
GN ORFNames=HCAG_02461 {ECO:0000313|EMBL:EDN05858.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN05858.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476656; EDN05858.1; -; Genomic_DNA.
DR AlphaFoldDB; A6QYK4; -.
DR STRING; 339724.A6QYK4; -.
DR VEuPathDB; FungiDB:HCAG_02461; -.
DR HOGENOM; CLU_016738_0_0_1; -.
DR OMA; HGKGFGH; -.
DR OrthoDB; 316032at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR Gene3D; 3.10.620.30; -; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR002931; Transglutaminase-like.
DR PANTHER; PTHR46333; CYTOKINESIS PROTEIN 3; 1.
DR PANTHER; PTHR46333:SF2; TRANSGLUTAMINASE-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01841; Transglut_core; 1.
DR SMART; SM00460; TGc; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT DOMAIN 401..474
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|SMART:SM00460"
FT REGION 12..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..94
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 72106 MW; B75D36663460AE51 CRC64;
MATIQERIAA LNQAHVGRGP VPSPPHEIRP DLPGSRPSMS GRYVAPANES RAPPVPVRDQ
EILPPPSITR TGQKSPTTTT KPRKPPPPLP TRKVTGEPSP ALPPRKPADT HTRRNSGDSS
LSATSISTRA TTSSSGNGKS PSIRSTSTES LTTRKLAPAW GETALPPLPP KRNTNTDGNP
TLKSRSSLGV LDSNCKTSSS SLSSLTPKLP LRSHSSNTND LPAIPPRKFA IKDLDAPPQL
PQRKIPPPAP SFKAIEKIRE SSFATLKNAS IHHGLVPNGD THGQKASGSP PPIPLGSRPD
LSKIQATKPR MPSCSSPSST GSTTVCMICR DFSGPDSHAA RFPRQSLPTQ DLSWLANQLT
APFSSLTDKA RAIFTWLHHN IDYNVDAFFN NKLKSSTPES TLTTGLAVCE GYAGLFERLA
TLAGLEARVI TGHGKGYGYT PLAPGSPKPP YDGNHAWNVV RIDNGQWKLI DSCWGAGNVS
GKGQPYNREF TPEYFTMSND EFGNKHFPAN PGDFYRDDGR PSISWEEYIS INPSCPNGVE
PPILYTGIKQ EHGIGERSLQ PRSRKIAVHQ PGPIRFQFGL ICEHWTLARS NIRAPCLFVL
FANGVDGSGK EYIPFHYVRG SDPGGGGDHC VTSFGDLKDT RGLSREEFLR GVGRKAMGFG
GIAEWELV
//
