ID A6R452_AJECN Unreviewed; 422 AA.
AC A6R452;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=HCAG_04410 {ECO:0000313|EMBL:EDN07900.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN07900.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476658; EDN07900.1; -; Genomic_DNA.
DR AlphaFoldDB; A6R452; -.
DR STRING; 339724.A6R452; -.
DR VEuPathDB; FungiDB:HCAG_04410; -.
DR HOGENOM; CLU_016304_6_2_1; -.
DR OMA; QEDHFHV; -.
DR OrthoDB; 129910at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12611; RRM1_NGR1_NAM8_like; 1.
DR CDD; cd12613; RRM2_NGR1_NAM8_like; 1.
DR CDD; cd12346; RRM3_NGR1_NAM8_like; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR47640:SF10; TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR47640; TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009297};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 93..168
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 183..262
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 311..383
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..406
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 44900 MW; 6BA84267F41C47EF CRC64;
MSFQNFDSFQ NQHGAADAAA AGTGAPAPAE SAMAGQSDPS PAPFQAPAYG EPASGSAQQA
GEAKPRFGML LNSIAPVNSF CLSSMWRNAC DGMGELEPWI DENFIRNLWF QMGEQVNVKM
IRDKFSGSNA GYCFVDFTTP AAAAKALTLS GTPIPNTSRT FKLNWASGGG LADRSREERG
PEFSIFVGDL GPEVNEYVLV SLFQSRFPSC KSAKIMTDPI SGMSRGYGFV RFSDETDQQR
ALTEMQGVYC GNRPMRISTA TPKNKGAGAG PGAMGMPGAG PAGMFPPMGG PPMGYYGAPQ
PMNQFTDPNN TTVFVGGLSG YVTEDELRSF FQGFGEITYV KIPPGKGCGF VQFVQRHAAE
MAINQMQGYP IGNSRVRLSW GRSQNNSGPA GSPYRPAPPP PMYSSMGMPP SHSYGGGFAP
MK
//
