ID   A6R6I1_AJECN            Unreviewed;       473 AA.
AC   A6R6I1;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   24-JAN-2024, entry version 68.
DE   RecName: Full=CRAL-TRIO domain-containing protein {ECO:0000259|PROSITE:PS50191};
GN   ORFNames=HCAG_05239 {ECO:0000313|EMBL:EDN08740.1};
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN08740.1, ECO:0000313|Proteomes:UP000009297};
RN   [1] {ECO:0000313|Proteomes:UP000009297}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
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DR   EMBL; CH476659; EDN08740.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6R6I1; -.
DR   STRING; 339724.A6R6I1; -.
DR   VEuPathDB; FungiDB:HCAG_05239; -.
DR   HOGENOM; CLU_016665_3_0_1; -.
DR   OMA; ISTMRWR; -.
DR   OrthoDB; 1539at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 2.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR011074; CRAL/TRIO_N_dom.
DR   InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR   PANTHER; PTHR46590:SF1; PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1; 1.
DR   PANTHER; PTHR46590; PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED; 1.
DR   Pfam; PF00650; CRAL_TRIO; 1.
DR   Pfam; PF03765; CRAL_TRIO_N; 1.
DR   SMART; SM01100; CRAL_TRIO_N; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR   SUPFAM; SSF46938; CRAL/TRIO N-terminal domain; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT   DOMAIN          228..333
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000259|PROSITE:PS50191"
FT   REGION          435..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   473 AA;  53342 MW;  5DD226345EC0CCAB CRC64;
     MSTDPALSGR VGHLTYQEET KLREFWAVLF KIFKISQAES VGVEWADSLL PLQKTQSTTA
     NTTDTSSVTS KKKTVTKKRF GFFGRSNETV EEKEEISTTS GQTVASQFKM ADDDDKYGLN
     KEFLTALASQ SPEELRMTFW NAIKQDNPDA FLLRFLRARK WDVQKALVML ISTLRWRSQE
     WKVDDEIVFK GEAAFHENSK SDDPIKKKEG EDMLHMIGIG EAYCRGKDKL GRPICYTNVI
     VFDMTDFGLA NMDYIPVKFI IKCFEANYPE SLGAILVHKA PWIFSSFWAI IKGWLDPVVA
     SKVHFTSNYQ ELEKFIAKEA IPRGLGGSDD YEYKYIEPKA GENDQMKDTA KAAALKDERA
     KIVDEFQKAT LDWINISSNA ADKAEDIKKK RQDIASRLSD FYWKLDPYIR ARSVYDRIKD
     AENAATAVTA TKTEASPVKA QEQTTVSEKS VTDTLGPQSH VVETPVVAAA AAN
//