ID A6R7V0_AJECN Unreviewed; 628 AA.
AC A6R7V0;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=Cell division control protein {ECO:0000256|PIRNR:PIRNR001767};
GN ORFNames=HCAG_06391 {ECO:0000313|EMBL:EDN09224.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN09224.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family.
CC {ECO:0000256|ARBA:ARBA00006184, ECO:0000256|PIRNR:PIRNR001767}.
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DR EMBL; CH476660; EDN09224.1; -; Genomic_DNA.
DR AlphaFoldDB; A6R7V0; -.
DR STRING; 339724.A6R7V0; -.
DR VEuPathDB; FungiDB:HCAG_06391; -.
DR HOGENOM; CLU_012774_2_0_1; -.
DR OMA; LFEWSLH; -.
DR OrthoDB; 118994at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR016314; Cdc6/18.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10763:SF26; CELL DIVISION CONTROL PROTEIN 6 HOMOLOG; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR Pfam; PF00004; AAA; 1.
DR PIRSF; PIRSF001767; Cdc6; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT DOMAIN 133..288
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 554..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..583
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 628 AA; 67660 MW; 068B938AB7406D4B CRC64;
MASSVLRKRL RHVDESISPP NTAIVVDENT RPLEFTTPRT PSRYRDALSV NNTKSVSQAV
PVTPRHRVQV SCLGKPLTPR TPRMIASPAN AQTVYTPARQ LFARSAAPGR LVGRESERQE
LTSFILNLVQ SRRGGCMYVS GPPGTGKSAL VDEVCQDLMI GVDMDKESVR IARINCATMT
SSKDIYAKIA DELCEDLQLF RKSRTELLAD MFVQKKRTSS STSTTISPTL YLVALDEIDH
LLTTDVETLY TLFEWSLQPH SRLVLIGIAN ALDLTDRFLP RLKSKNMKPR LLPFLPYTAS
QIADIVSTRL RSLLPSSNTA ASATTVSEDF TPFLQPAAIQ LCARKVASQT GDLRKAFDIV
RRTIDLIEQE TRQKQNSSSC RSPTKVPLVE NVNLASPLIS PPDTPSSALS STARATATGY
TAATAPRATV AHVARVTANT FGHGTVQRLQ GLNLQQKVAL CVLIVLGRRK TDFDNGDRKR
GMHNGTLSTT SSMVAGAAGA AGAAAAAAPT VNELFVTYSA LCRRDKILQP LAATEFRDVV
GSLETLGLVG EVQAQGRGRA STSTTSRVGG RSMGTSTPSK PKTPTRRAGA GPGADERKLV
CFVGEGEVEK LICGEGGAIL RGLFRAEA
//
