ID   A6R8E7_AJECN            Unreviewed;       754 AA.
AC   A6R8E7;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   24-JAN-2024, entry version 52.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 3 {ECO:0000256|ARBA:ARBA00020976};
DE   AltName: Full=Component of oligomeric Golgi complex 3 {ECO:0000256|ARBA:ARBA00031339};
GN   ORFNames=HCAG_06588 {ECO:0000313|EMBL:EDN09421.1};
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN09421.1, ECO:0000313|Proteomes:UP000009297};
RN   [1] {ECO:0000313|Proteomes:UP000009297}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- SIMILARITY: Belongs to the COG3 family.
CC       {ECO:0000256|ARBA:ARBA00009936}.
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DR   EMBL; CH476660; EDN09421.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6R8E7; -.
DR   STRING; 339724.A6R8E7; -.
DR   VEuPathDB; FungiDB:HCAG_06588; -.
DR   HOGENOM; CLU_011639_0_0_1; -.
DR   OMA; DEFELWG; -.
DR   OrthoDB; 52120at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   GO; GO:0005801; C:cis-Golgi network; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   InterPro; IPR048685; COG3_C.
DR   InterPro; IPR048320; COG3_N.
DR   InterPro; IPR007265; COG_su3.
DR   PANTHER; PTHR13302; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3; 1.
DR   PANTHER; PTHR13302:SF8; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3; 1.
DR   Pfam; PF20671; COG3_C; 1.
DR   Pfam; PF04136; COG3_N; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009297};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          5..151
FT                   /note="Conserved oligomeric Golgi complex subunit 3 N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04136"
FT   DOMAIN          171..532
FT                   /note="Conserved oligomeric Golgi complex subunit 3 C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF20671"
FT   REGION          388..418
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          719..754
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        722..744
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   754 AA;  85152 MW;  85F26DAB193B2CE8 CRC64;
     MDRSCLDELE TSKLHLDSLL TDTTSTLELL STLSESFKSV EAQTSAFRQQ CEGLLSAQLR
     SSKLADEIHE NLQYYDLLDP VSRRLNAPGA GNSVRTKDFS DMLKRLDESL DYMQTHKPEQ
     KESETYRSRY HLLLTRALTL IRGHFVSTLR EISSGVAKRI ADRQLNDTTM SALLYAKFRV
     GAADLKAIGL EIQKRAVPPV DSEQGTEPEY QSLLNELHTS FSATRGKLVI PVLRKRLNDI
     AQAPSTSKDL VVFARASISY IRGICLDEFE LWGQWFHGQQ GLYDFLESVC EPLYDHLRPR
     IIRETKLIKL CQLCSLLQTR YLSDPEDEGE CADPTQLDFS ILIQPALEDA QTRLVFRTQA
     ILRDEIEKYK PRPEDLDYPA RNRSVLLQGP ENNESRTVPH RKASIAGPTT PLPKMPMVVD
     EDIDSPQEKD VRWDFDSRAA FEGWYPTLRK AVWLLSRIYR LVNSTVFDDL AHQVVHQTTI
     SLHAASSQIS TKASPADAQL FLIKHLLLLK QQIVAFDIEF VSPDIYFDFS GVTNTFWELR
     QRGGLFNPRN LMRLVGGGLL PRVVENMLDA KAELDGRLRT VINDFTNSFS SKMTTPLASP
     ARSTNRSESY SNALRLTCKA IEKEVPHLRR ILDQYLDDVR TKETLVGAVQ DSVIQAYEDF
     YNSYISTLEG GKDGVTSNKL STMEKSRKAQ EDGVWDVDTF TGWSETVFHV GVAGLASSEG
     RVSDLSEEDG DVRRGSDDIS SSGERQRPSR NGSM
//