ID A6RAG1_AJECN Unreviewed; 608 AA.
AC A6RAG1;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE RecName: Full=UspA domain-containing protein {ECO:0000259|Pfam:PF00582};
GN ORFNames=HCAG_05949 {ECO:0000313|EMBL:EDN10146.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN10146.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476661; EDN10146.1; -; Genomic_DNA.
DR AlphaFoldDB; A6RAG1; -.
DR STRING; 339724.A6RAG1; -.
DR VEuPathDB; FungiDB:HCAG_05949; -.
DR HOGENOM; CLU_015980_1_0_1; -.
DR OMA; CKNPRHL; -.
DR OrthoDB; 1368087at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR CDD; cd00293; USP_Like; 1.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR006015; Universal_stress_UspA.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR46100; IMP2'P; 1.
DR PANTHER; PTHR46100:SF4; USP DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR01438; UNVRSLSTRESS.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT DOMAIN 501..576
FT /note="UspA"
FT /evidence="ECO:0000259|Pfam:PF00582"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..98
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..182
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..442
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 608 AA; 64242 MW; B5E1483F937DEAAD CRC64;
MLPSIPSQAR PKRVSQGGKK TANHATNATH ANSMAAVMSG QELGSLPGFT RGRDTMRHGG
TVGGSARHSK SPSSRLARSR SPGGGLFNTN SLNPKPVPGT FVTDTGKVIH LDHAYRQLSN
AALSRSGGTL SKFQKSSTSR ERGEDAVSES GDSRLQEDYY SGEETFSGEN SSDEENDYSS
SAEEDWSAEI QRGRRRSRKK SDSEENDLNK NGPQKVRSLL AAAEEERKKV SATYKVKSLL
DPEPATGKAA TEKPMIKKTG VVHPTTSFDH VGSGPNTPAG SDDEAQYRDF KKAQNLSIYM
SPIDQSVPNR VIRTIVRGEF TRVQEEARQN RRMRLRTYLV ATDLSDESVY ALEWTIGTIL
RDGDTLYAVY AIDEETSGHG SGKGGEPDST SSVQIGDGIK VMLDTAAVVG LQTKKTAENL
TGASPLPSAN TSSTQVSGGS GSSGGGGGGG GGGGGGGGGG GGGGGGGGGS GGTDSKTGSV
DSRAVSKFEA ERFRAIEGIS QTVVRLLKKT RLQVRVAVEV IHCNSPKHLI TEAIDGLEPT
LVILGSRGRS ALKGVLLGSF SNYLVTKSSV PVMVARKKLK KHTKFKRANV RLLNNLTTPK
KLVYAKID
//
