ID A6RAS4_AJECN Unreviewed; 356 AA.
AC A6RAS4;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN ORFNames=HCAG_06062 {ECO:0000313|EMBL:EDN10259.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN10259.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476661; EDN10259.1; -; Genomic_DNA.
DR AlphaFoldDB; A6RAS4; -.
DR STRING; 339724.A6RAS4; -.
DR VEuPathDB; FungiDB:HCAG_06062; -.
DR HOGENOM; CLU_778381_0_0_1; -.
DR OMA; VEVKGWQ; -.
DR OrthoDB; 1891044at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR10555:SF170; FI18122P1; 1.
DR PANTHER; PTHR10555; SORTING NEXIN; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT DOMAIN 187..303
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 12..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 39247 MW; CBAB2E3BFBBDB34B CRC64;
MVPFARKINY AASQTAKYDR KMDLVGGESP WGDVPSQSAP TENQESSATA NDSEQPAQTT
LTTRRSPPAR GPRTPRKINA QATRLEVVDD SLDPLGPLGD KSFPSILSYP DQGPTPPRKE
LFSSRNVRPA SSTSQSSTGG LMDSVDLDDD GQAARARIKG PPPVQSPVDA PKRQSQPSMP
VEQAAKPSFE ITVGDPHKVG DIASSHIVYQ VRTKTTSKAY RQPEFTVSRR YRDFLWLYNS
LHGNNPGVVV PPPPEKQAVG RFDTNFVESR RAALERMLNK IAAHHILQHD GDLKIFLESD
TFNLDVKNKE NREPDIGQNK GMLSSLGISV GGPGKFVEHD DWFHDRKYTL TPLRIS
//
