ID A6RGL9_AJECN Unreviewed; 910 AA.
AC A6RGL9;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE RecName: Full=PHD-type domain-containing protein {ECO:0000259|Pfam:PF00628};
GN ORFNames=HCAG_08786 {ECO:0000313|EMBL:EDN05131.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN05131.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CH476666; EDN05131.1; -; Genomic_DNA.
DR AlphaFoldDB; A6RGL9; -.
DR STRING; 339724.A6RGL9; -.
DR VEuPathDB; FungiDB:HCAG_08786; -.
DR HOGENOM; CLU_011451_0_0_1; -.
DR OMA; CVNIDPR; -.
DR OrthoDB; 124870at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR037869; Spp1/CFP1.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46174; CXXC-TYPE ZINC FINGER PROTEIN 1; 1.
DR PANTHER; PTHR46174:SF1; CXXC-TYPE ZINC FINGER PROTEIN 1; 1.
DR Pfam; PF00628; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009297};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 483..521
FT /note="PHD-type"
FT /evidence="ECO:0000259|Pfam:PF00628"
FT REGION 350..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 569..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..709
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 734..761
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 355..396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 629..648
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..709
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 910 AA; 101854 MW; DEEDA45491282F02 CRC64;
MGLLPSEAAT MLTDLDVNPY ETNAEKLPPS DRFLARHPHY GRYRPSSNDF EPDPIHCNSN
DDESLRYWEA VLARCDEKTR INTLAAGKRD TFALGSVIVK SDHNSTEPTG DYSVADENEI
YAIKIAEKIL PDIQLPEIYL RTKLNGRDVL VQSRIPGVSL EVAWPYLTRK QKENFKKQAR
NIIQRINSVN DGRSSPSYVV KGNRPKEEHR LQQAEYDILF GPDSDSNQNL SFTNNNMVPA
NIIVDKDTIV GIIGWYSAGY FGWDRAKNIH HKIRCLDSAD VSSDGGVSIP DAFWRDLYDI
SVDHSASRNL DLKSEIKIEP PSLNLESIPN GSAADIPVLT KEPWTPRKIT DLKCESMSRA
SSTERSSPVT SAKPLDSSPG SSTKKRAVSS TKKGNPTRKP AIKKRKLNDT ESVDGAASPL
RRSATPISSR ASKAPVKNRK QSSLSVAGSP VPETKKAIKA PESQQDVDGD DVYEDEDSTE
LFCICRKPDN HTWMIGCDGG CEDWFHGKCV KINQTDADLI DKYISKKGIH TTWKRMCRLP
GCRRPARISG GMVPSKYCSD EHGREFMRQK ASLSKQGSAA GASPAANTSA TDSRSRGSSV
VVGKRRQKGV HRDDTEPDGV QPDPGVSNPR DEDEEDEEDV EDEAETENGH TEDLGSRGGI
LSKNDLKAVV TGVASAQEFR ELGDNILPPS VTEKLTPSSS IPLEDSSSKF RTNTVSQDVD
QIDFDLDAHQ IQFTANERQH IDNLRQKRRE LRGQLEMLQD RDTFLTLIRQ RAKTILEHIR
QTDPKTSASS WKDICGYDRR LAWSDDEFDE WRLSEEGKEA LHSGALKTAD PEPDGFGDIE
MQDADRDDMT VDRIARGVCI KKRCERHRQW VKVQQQDIQH EERVAREELE KCEKDTKDVI
GRIVLRAYGE
//
