ID   A6RHM9_AJECN            Unreviewed;       365 AA.
AC   A6RHM9;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   RecName: Full=Aminoglycoside phosphotransferase domain-containing protein {ECO:0000259|Pfam:PF01636};
GN   ORFNames=HCAG_09099 {ECO:0000313|EMBL:EDN07496.1};
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN07496.1, ECO:0000313|Proteomes:UP000009297};
RN   [1] {ECO:0000313|Proteomes:UP000009297}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- SIMILARITY: Belongs to the aminoglycoside phosphotransferase family.
CC       {ECO:0000256|ARBA:ARBA00006219}.
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DR   EMBL; CH476684; EDN07496.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6RHM9; -.
DR   STRING; 339724.A6RHM9; -.
DR   VEuPathDB; FungiDB:HCAG_09099; -.
DR   HOGENOM; CLU_021768_0_0_1; -.
DR   OMA; EWRNKWI; -.
DR   OrthoDB; 2655425at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd05120; APH_ChoK_like; 1.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   InterPro; IPR002575; Aminoglycoside_PTrfase.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   PANTHER; PTHR21310; AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED; 1.
DR   PANTHER; PTHR21310:SF56; APH DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01636; APH; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT   DOMAIN          122..344
FT                   /note="Aminoglycoside phosphotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF01636"
SQ   SEQUENCE   365 AA;  41843 MW;  6C3E11421E54963A CRC64;
     MGTVRKLILD QQQILNAQAK PLNLKVIGNL IPPTSHNSLS SRNSWYYQQP ETIHNKVPIK
     QQIQPSATLN ATQTEMDFLD SSFFTKAGHK SLPTAAEVGS LSEQFNKHPR PAPVKFEHLN
     LLVKFGPSVA VEEALTLRML RTSFAEKIPV PEVYGWRVYQ NSVFIYMELI QGDTLHDRWD
     SLNELDRNFI CGQLREIISS LRQIEPDPCD SFIGSINRAR LHDYVFATIP QSGPFKNVKA
     FNDWFSSLPQ SWLPDSKRYR DPYRDYLPDD GAIRLTHGDL HRGNILISPA GRPRVLAVVD
     WAHAGWYPEY WEYCKALYTS DYKGEWRNVW IPKFLTAYEP EFAAFGEYVL QIGAVEAIAK
     CQKPK
//