ID A6TIA6_KLEP7 Unreviewed; 227 AA.
AC A6TIA6;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Probable transcriptional regulatory protein(Silver resistance) {ECO:0000313|EMBL:ABR80329.1};
GN Name=silR {ECO:0000313|EMBL:ABR80329.1};
GN ORFNames=KPN_pKPN3p05950 {ECO:0000313|EMBL:ABR80329.1};
OS Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OG Plasmid pKPN3 {ECO:0000313|EMBL:ABR80329.1,
OG ECO:0000313|Proteomes:UP000000265}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=272620 {ECO:0000313|EMBL:ABR80329.1, ECO:0000313|Proteomes:UP000000265};
RN [1] {ECO:0000313|Proteomes:UP000000265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RC PLASMID=pKPN3 {ECO:0000313|Proteomes:UP000000265};
RG The Klebsiella pneumonia Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000648; ABR80329.1; -; Genomic_DNA.
DR AlphaFoldDB; A6TIA6; -.
DR EnsemblBacteria; ABR80329; ABR80329; KPN_pKPN3p05950.
DR KEGG; kpn:KPN_pKPN3p05950; -.
DR HOGENOM; CLU_000445_30_1_6; -.
DR Proteomes; UP000000265; Plasmid pKPN3.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd19935; REC_OmpR_CusR-like; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.250.690; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR006291; CusR-like.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR039420; WalR-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR01387; cztR_silR_copR; 1.
DR PANTHER; PTHR48111; REGULATOR OF RPOS; 1.
DR PANTHER; PTHR48111:SF41; TRANSCRIPTIONAL REGULATORY PROTEIN CUSR-RELATED; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Plasmid {ECO:0000313|EMBL:ABR80329.1}.
FT DOMAIN 3..117
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 126..224
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 126..224
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT MOD_RES 52
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 227 AA; 25308 MW; E8EB15CD8942F6EC CRC64;
MMKILIVEDE IKTGEYLSKG LTEAGFVVDH ADNGLTGYHL AMTAEYDLVI LDIMLPDVNG
WDIIRMLRSA GKGMPVLLLT ALGTIEHRVK GLELGADDYL VKPFAFAELL ARVRTLLRRG
NTMITESQLK VADLSVDLVS RKVSRAGNRI VLTSKEFSLL EFFIRHQGEV LPRSLIASQV
WDMNFDSDTN AIDVAVKRLR AKIDNDYGTK LIQTVRGVGY MLEIPDA
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