ID A6U7Y1_SINMW Unreviewed; 134 AA.
AC A6U7Y1;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Methylmalonyl-CoA epimerase {ECO:0000313|EMBL:ABR59761.1};
DE EC=5.1.99.1 {ECO:0000313|EMBL:ABR59761.1};
GN OrderedLocusNames=Smed_0906 {ECO:0000313|EMBL:ABR59761.1};
OS Sinorhizobium medicae (strain WSM419) (Ensifer medicae).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=366394 {ECO:0000313|EMBL:ABR59761.1, ECO:0000313|Proteomes:UP000001108};
RN [1] {ECO:0000313|Proteomes:UP000001108}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM419 {ECO:0000313|Proteomes:UP000001108};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G.,
RA Richardson P.;
RT "Complete sequence of Sinorhizobium medicae WSM419 chromosome.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABR59761.1, ECO:0000313|Proteomes:UP000001108}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM419 {ECO:0000313|EMBL:ABR59761.1,
RC ECO:0000313|Proteomes:UP000001108};
RX PubMed=21304680; DOI=10.4056/sigs.43526;
RA Reeve W., Chain P., O'Hara G., Ardley J., Nandesena K., Brau L., Tiwari R.,
RA Malfatti S., Kiss H., Lapidus A., Copeland A., Nolan M., Land M.,
RA Hauser L., Chang Y.J., Ivanova N., Mavromatis K., Markowitz V.,
RA Kyrpides N., Gollagher M., Yates R., Dilworth M., Howieson J.;
RT "Complete genome sequence of the Medicago microsymbiont Ensifer
RT (Sinorhizobium) medicae strain WSM419.";
RL Stand. Genomic Sci. 2:77-86(2010).
CC -!- SIMILARITY: Belongs to the methylmalonyl-CoA epimerase family.
CC {ECO:0000256|ARBA:ARBA00009308}.
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DR EMBL; CP000738; ABR59761.1; -; Genomic_DNA.
DR RefSeq; WP_011975098.1; NC_009636.1.
DR RefSeq; YP_001326596.1; NC_009636.1.
DR AlphaFoldDB; A6U7Y1; -.
DR STRING; 366394.Smed_0906; -.
DR GeneID; 61612258; -.
DR KEGG; smd:Smed_0906; -.
DR PATRIC; fig|366394.8.peg.4020; -.
DR eggNOG; COG0346; Bacteria.
DR HOGENOM; CLU_046006_5_0_5; -.
DR OrthoDB; 9788468at2; -.
DR Proteomes; UP000001108; Chromosome.
DR GO; GO:0004493; F:methylmalonyl-CoA epimerase activity; IEA:UniProtKB-EC.
DR CDD; cd07249; MMCE; 1.
DR Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 1.
DR InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR InterPro; IPR017515; MeMalonyl-CoA_epimerase.
DR InterPro; IPR037523; VOC.
DR NCBIfam; TIGR03081; metmalonyl_epim; 1.
DR PANTHER; PTHR43048; METHYLMALONYL-COA EPIMERASE; 1.
DR PANTHER; PTHR43048:SF3; METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13669; Glyoxalase_4; 1.
DR SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 1.
DR PROSITE; PS51819; VOC; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:ABR59761.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 4..134
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
SQ SEQUENCE 134 AA; 14234 MW; 54FC46D901435250 CRC64;
MLGKVNHVAI AVPDLSAAVE SYRSTLGALV TEPQALPEHG VTVVFVALPN TKVELLEPLG
DASPVSAFLE KNPAGGMHHI CYEVEDIIAA RDRLKDAGAR ILGDGNPKIG AHGKPVLFLH
PKDFQGTLIE LEQV
//
