ID A6UC82_SINMW Unreviewed; 853 AA.
AC A6UC82;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=FAD dependent oxidoreductase {ECO:0000313|EMBL:ABR61262.1};
GN OrderedLocusNames=Smed_2430 {ECO:0000313|EMBL:ABR61262.1};
OS Sinorhizobium medicae (strain WSM419) (Ensifer medicae).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=366394 {ECO:0000313|EMBL:ABR61262.1, ECO:0000313|Proteomes:UP000001108};
RN [1] {ECO:0000313|Proteomes:UP000001108}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM419 {ECO:0000313|Proteomes:UP000001108};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G.,
RA Richardson P.;
RT "Complete sequence of Sinorhizobium medicae WSM419 chromosome.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABR61262.1, ECO:0000313|Proteomes:UP000001108}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM419 {ECO:0000313|EMBL:ABR61262.1,
RC ECO:0000313|Proteomes:UP000001108};
RX PubMed=21304680; DOI=10.4056/sigs.43526;
RA Reeve W., Chain P., O'Hara G., Ardley J., Nandesena K., Brau L., Tiwari R.,
RA Malfatti S., Kiss H., Lapidus A., Copeland A., Nolan M., Land M.,
RA Hauser L., Chang Y.J., Ivanova N., Mavromatis K., Markowitz V.,
RA Kyrpides N., Gollagher M., Yates R., Dilworth M., Howieson J.;
RT "Complete genome sequence of the Medicago microsymbiont Ensifer
RT (Sinorhizobium) medicae strain WSM419.";
RL Stand. Genomic Sci. 2:77-86(2010).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; CP000738; ABR61262.1; -; Genomic_DNA.
DR RefSeq; WP_012066653.1; NC_009636.1.
DR RefSeq; YP_001328097.1; NC_009636.1.
DR AlphaFoldDB; A6UC82; -.
DR STRING; 366394.Smed_2430; -.
DR GeneID; 61611330; -.
DR KEGG; smd:Smed_2430; -.
DR PATRIC; fig|366394.8.peg.5616; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR HOGENOM; CLU_007884_11_2_5; -.
DR OrthoDB; 9804379at2; -.
DR Proteomes; UP000001108; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
FT DOMAIN 9..382
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 385..441
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 443..722
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 791..836
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 853 AA; 95605 MW; B0791D4B85C30F4C CRC64;
MAEFPEKAKV VIVGLGGIVG ASIAHHLIER GWDDIVGIDK SGIPTDIGST AHASDFCYTT
SHDYLSVWTT QYSIDFFDRM GHYSRIGGLE VARTGDDVWM EEIKRKLSSA KAFGTRAHYV
SPAEIKKLFP LIEEDQVMGG MFDPDAGLVV PRSQTVAGKL VDAAEKSGKL RVFGNTPATA
LLVENGRIKG VVTHRGTILA DHVVVCAGIW GRLIAEMVGE DLPVMPVDHP LTFFGPYNEF
EGTGKEIGFP LLRDQGNSAY MRDTGDPKTT EGGQIEWGYY ETTNPRLCHP RDILEKHQAR
LSPSQRDLEM EQIIEPLERA MELTPILGEL GYNESHSFNG LLQVSAAGGP SCGESQKVRG
LWYCVAIWVK DGPGYGKLIA DWMTDGRTEI DHASIDYARF YPHQLEETFI EQRCFEAAQK
IYFPAVHPRE PYAGGRNVKR SPFYEREKEL GGYFMELGGW ERAHGYAANE HLLEKYGDRV
PVRENEWDSR HFWRVSNAEH LAMSEDCGIV NLSHFHMVDI EGPDHVELLE WLCAAKIGGD
GNIGKGIYTH FLDDEGMVRA DFTVFRMADR CRLVNGADAG PRDFHYMRRV AEDRGLDVRI
TDVSERFTTI GIWGPNARET LKRVVADPAG LDPENFPFAA IRQMEIAGKP VSAFRISYVG
EQGWELHMKY EDGLAVWDAL RATGVMAFGV ETYANSRRME KSLRLQNADL LTQYNLIEAD
LARPKVKEAD FRGKAKHLEY KAREHQPAML CTLVMTENTD GNGVRRYPVG NLPVMDPETG
DVLVDELGRR SYTTSIAYGP TIGKNIALAY LPWSYCQVGR RLHVEYFAET YPVEVAGVGY
KPLYDPENLK PRT
//
