ID   A6UEQ8_SINMW            Unreviewed;       789 AA.
AC   A6UEQ8;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Glycine cleavage T protein (Aminomethyl transferase) {ECO:0000313|EMBL:ABR62138.1};
GN   OrderedLocusNames=Smed_3316 {ECO:0000313|EMBL:ABR62138.1};
OS   Sinorhizobium medicae (strain WSM419) (Ensifer medicae).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=366394 {ECO:0000313|EMBL:ABR62138.1, ECO:0000313|Proteomes:UP000001108};
RN   [1] {ECO:0000313|Proteomes:UP000001108}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM419 {ECO:0000313|Proteomes:UP000001108};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G.,
RA   Richardson P.;
RT   "Complete sequence of Sinorhizobium medicae WSM419 chromosome.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABR62138.1, ECO:0000313|Proteomes:UP000001108}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM419 {ECO:0000313|EMBL:ABR62138.1,
RC   ECO:0000313|Proteomes:UP000001108};
RX   PubMed=21304680; DOI=10.4056/sigs.43526;
RA   Reeve W., Chain P., O'Hara G., Ardley J., Nandesena K., Brau L., Tiwari R.,
RA   Malfatti S., Kiss H., Lapidus A., Copeland A., Nolan M., Land M.,
RA   Hauser L., Chang Y.J., Ivanova N., Mavromatis K., Markowitz V.,
RA   Kyrpides N., Gollagher M., Yates R., Dilworth M., Howieson J.;
RT   "Complete genome sequence of the Medicago microsymbiont Ensifer
RT   (Sinorhizobium) medicae strain WSM419.";
RL   Stand. Genomic Sci. 2:77-86(2010).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000738; ABR62138.1; -; Genomic_DNA.
DR   RefSeq; WP_012067519.1; NC_009636.1.
DR   RefSeq; YP_001328973.1; NC_009636.1.
DR   AlphaFoldDB; A6UEQ8; -.
DR   STRING; 366394.Smed_3316; -.
DR   KEGG; smd:Smed_3316; -.
DR   PATRIC; fig|366394.8.peg.6558; -.
DR   eggNOG; COG0404; Bacteria.
DR   eggNOG; COG3665; Bacteria.
DR   HOGENOM; CLU_019604_0_0_5; -.
DR   OrthoDB; 9800828at2; -.
DR   Proteomes; UP000001108; Chromosome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR018959; DUF1989.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF09347; DUF1989; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   4: Predicted;
KW   Transferase {ECO:0000313|EMBL:ABR62138.1}.
FT   DOMAIN          193..361
FT                   /note="DUF1989"
FT                   /evidence="ECO:0000259|Pfam:PF09347"
FT   DOMAIN          418..674
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          702..781
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   789 AA;  87488 MW;  85B75DABAAEFD289 CRC64;
     MEDRHPGMLG GRPVSASIIR YPGIPALPKD RERYRCKGGG SLVVRVEAGD HVTVTDIEGC
     QACELSFLDE DGRFQSAGLG TAFTNDAEGL KTILSLEEES SLRTRNALRR RGADLSTAGA
     LRVFGERSTP GSKAEFTTTM KGLLIVAAPG KAMAPEAQDT ATPIETMIRR SRPIRDYTSA
     LPEPLADPIH DIRIKAATAS AYFVRAGEFI QIIDVYGRQC TDFQAFAARK VDKGLDRALD
     STVTRTLLGR SYPAPGLPSK AFDRDFEPLV EIVQDTVGRH DAFATACNAR YYDDMGYPGH
     VNCTDNFNAA LAPYGISGRK GWEALNYFYN TSIDHNNQLY LDEPWSRPGD YVLMRAVTDL
     ICVSSSCPDD IDAANGWDPT DIHVRTFSGN EQFSRAVAYR MTPDADPEMT RETAFHPRFS
     ALTRDYAEYR GYWLPNRFSS EGPIEEYWAC RERAAVIDLS PLRKFEVTGP DAEELLQYCL
     TRDVRKLSTG QVVYSAMCYE HGGMIDDGTL FRLGDKNFRW IGGDDYSGIW LREQAEKKGF
     RAWVRSSTDQ MHNIAVQGPK SRDILREIIW TAPRQSTISE LEWFRFAVGR IGGFEGAPVV
     VSRTGYTGEL GYEIFCHPKD ALTVFDAVWQ AGEPHGMKPM GLEALDMVRI EAGLIFAHYD
     FDDQTDPFEA GIGFTVPLKS KPDDFIGREA LMRRKESPRQ LMVGLDVLAN EAIGHGDCVH
     VGRAQIGVVT SATRSPVLGK TIALARIDVT HATVGTQVEI GKLDGQQKRL PAAVVPLSHY
     DPQKKRPRS
//