ID A6UUD0_META3 Unreviewed; 245 AA.
AC A6UUD0;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Anaerobic ribonucleoside-triphosphate reductase activating protein {ECO:0000313|EMBL:ABR56102.1};
GN OrderedLocusNames=Maeo_0516 {ECO:0000313|EMBL:ABR56102.1};
OS Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 /
OS Nankai-3).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanococcaceae; Methanococcus.
OX NCBI_TaxID=419665 {ECO:0000313|EMBL:ABR56102.1, ECO:0000313|Proteomes:UP000001106};
RN [1] {ECO:0000313|EMBL:ABR56102.1, ECO:0000313|Proteomes:UP000001106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3
RC {ECO:0000313|Proteomes:UP000001106};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A.,
RA Sieprawska-Lupa M., Whitman W.B., Richardson P.;
RT "Complete sequence of Methanococcus aeolicus Nankai-3.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP000743; ABR56102.1; -; Genomic_DNA.
DR RefSeq; WP_011973234.1; NC_009635.1.
DR AlphaFoldDB; A6UUD0; -.
DR STRING; 419665.Maeo_0516; -.
DR GeneID; 75305221; -.
DR KEGG; mae:Maeo_0516; -.
DR eggNOG; arCOG00952; Archaea.
DR HOGENOM; CLU_078147_2_1_2; -.
DR OrthoDB; 371936at2157; -.
DR Proteomes; UP000001106; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR012840; NrdG2.
DR InterPro; IPR034457; Organic_radical-activating.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR02495; NrdG2; 1.
DR PANTHER; PTHR30352:SF13; GLYCYL-RADICAL ENZYME ACTIVATING ENZYME YJJW-RELATED; 1.
DR PANTHER; PTHR30352; PYRUVATE FORMATE-LYASE-ACTIVATING ENZYME; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 2.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SFLD; SFLDG01094; Uncharacterised_Radical_SAM_Su; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 13..227
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 245 AA; 27789 MW; 1CB37EBD6FC28988 CRC64;
MKIFGIVDIS TIDYPKMCSA VVFLSGCNML CGYCHNYEHM LDNTRNIDMS PKEVFDKIDL
IFADALVISG GEPTLQPEGV KELCKLAKNE GLAVKLDTNG TSVDIVKDII DNKLIDYIAL
DVKCGFDKYE KIARYNGSII KKNILEIINY CISNNVFIEC RTTVVPDLMD KQDIVEIAKT
VKDCNLYAIQ QMDCHHSYTE EYQKMRHIKT DELMELGKIA EKYVGEDTSI IIRSNNEVFK
VKTGK
//
