ID A6VKN2_ACTSZ Unreviewed; 796 AA.
AC A6VKN2;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Alpha-glucosidase {ECO:0000313|EMBL:ABR73529.1};
DE EC=3.2.1.20 {ECO:0000313|EMBL:ABR73529.1};
GN OrderedLocusNames=Asuc_0149 {ECO:0000313|EMBL:ABR73529.1};
OS Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 /
OS 130Z).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Actinobacillus.
OX NCBI_TaxID=339671 {ECO:0000313|EMBL:ABR73529.1, ECO:0000313|Proteomes:UP000001114};
RN [1] {ECO:0000313|Proteomes:UP000001114}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z
RC {ECO:0000313|Proteomes:UP000001114};
RX PubMed=21118570; DOI=10.1186/1471-2164-11-680;
RA McKinlay J.B., Laivenieks M., Schindler B.D., McKinlay A.A.,
RA Siddaramappa S., Challacombe J.F., Lowry S.R., Clum A., Lapidus A.L.,
RA Burkhart K.B., Harkins V., Vieille C.;
RT "A genomic perspective on the potential of Actinobacillus succinogenes for
RT industrial succinate production.";
RL BMC Genomics 11:680-680(2010).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000746; ABR73529.1; -; Genomic_DNA.
DR AlphaFoldDB; A6VKN2; -.
DR STRING; 339671.Asuc_0149; -.
DR CAZy; GH31; Glycoside Hydrolase Family 31.
DR KEGG; asu:Asuc_0149; -.
DR eggNOG; COG1501; Bacteria.
DR HOGENOM; CLU_000631_7_2_6; -.
DR OrthoDB; 176168at2; -.
DR Proteomes; UP000001114; Chromosome.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0032450; F:maltose alpha-glucosidase activity; IEA:UniProtKB-EC.
DR CDD; cd06599; GH31_glycosidase_Aec37; 1.
DR CDD; cd14752; GH31_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR InterPro; IPR033403; DUF5110.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR PANTHER; PTHR22762:SF165; PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06560)-RELATED; 1.
DR Pfam; PF17137; DUF5110; 1.
DR Pfam; PF13802; Gal_mutarotas_2; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361185, ECO:0000313|EMBL:ABR73529.1};
KW Hydrolase {ECO:0000256|RuleBase:RU361185, ECO:0000313|EMBL:ABR73529.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001114}.
FT DOMAIN 27..213
FT /note="Glycoside hydrolase family 31 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13802"
FT DOMAIN 263..586
FT /note="Glycoside hydrolase family 31 TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01055"
FT DOMAIN 596..683
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
FT DOMAIN 701..767
FT /note="DUF5110"
FT /evidence="ECO:0000259|Pfam:PF17137"
SQ SEQUENCE 796 AA; 92434 MW; 07ED18D26C016F2F CRC64;
MKTLKSAQFL RQEGNRVDIQ CERDYIMHIF VLEQDVIRVA FTHKNAFKLD RTWAIAPNQE
DVPFEGRDRI STAGFSLPNY QLNFTNDVIE VATDLLKIRI NQPLALEWFY KKEDEWLPLM
QERKTGAYQF GVSNDKIAHF IARSLDENCY GLGEKAGDLN RKGRRFEMRN LDAMGYNAEK
TDPLYKHIPF YITRKNDVSY GIYYDNLAQC WFDLGNELDN YHTAYKSYRA EDGDMDYYVI
LGPSTLDVTK KYTALTGGTI FGPRWGLGYS GSTMSYTDAD DAQEQLKKFV DLCKQHDIPC
DSFQLSSGYT SINGKRYVFN WNYDKIPEPL KMSAHFREAG MHLAANIKPC MLQDHPRYKE
AETLGLFIKD SETGLPERSV FWDDEGSHLD FTNPATVKWW KDNVKEQLLE RGIGSTWNDN
NEYEIWDEQA KCAGFGKEIP INLIRALHPL LMMRSSYEAQ KEFAPNERPY LISRSGCAGM
NRYVQTWSGD NRTGWNTLRY NIRMGLGMSL SGLYNVGHDV GGFAGDKPEP ELFVRWVQNG
IFHPRFTIHS WNDDKTVNEP WMYPEVTNII RDTIKLRYRL MPYIYNIFWQ SHKQLEPMLR
PTFLDHENDA NTYAETDDYL FGRELLVASV VEKGQRNREV YLPQNHAGWY DFYHHTYYEP
GQKINVDAPL ERIPLFVKAG TVIPMSERTA YSKPEADTAR QLAVYPLKQD GELQCSIFDD
DGLTYQYQKG EYLQLNITLG STQDTVYMDI RKQGNWKPAY QALKLTLPAN ETRTFLVNGN
EFRPGTELSL ENIREI
//
