ID A6ZWD2_YEAS7 Unreviewed; 557 AA.
AC A6ZWD2;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Vacuolar sorting protein {ECO:0000313|EMBL:EDN61024.1};
GN Name=VPS30 {ECO:0000313|EMBL:EDN61024.1};
GN ORFNames=SCY_5609 {ECO:0000313|EMBL:EDN61024.1};
OS Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=307796 {ECO:0000313|EMBL:EDN61024.1, ECO:0000313|Proteomes:UP000007060};
RN [1] {ECO:0000313|EMBL:EDN61024.1, ECO:0000313|Proteomes:UP000007060}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YJM789 {ECO:0000313|EMBL:EDN61024.1,
RC ECO:0000313|Proteomes:UP000007060};
RX PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA Steinmetz L.M.;
RT "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT strain YJM789.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC -!- SIMILARITY: Belongs to the beclin family.
CC {ECO:0000256|ARBA:ARBA00005965}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDN61024.1}.
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DR EMBL; AAFW02000135; EDN61024.1; -; Genomic_DNA.
DR AlphaFoldDB; A6ZWD2; -.
DR HOGENOM; CLU_024219_3_2_1; -.
DR Proteomes; UP000007060; Unassembled WGS sequence.
DR GO; GO:0006914; P:autophagy; IEA:InterPro.
DR Gene3D; 6.10.250.3110; -; 1.
DR Gene3D; 1.10.418.40; Autophagy protein 6/Beclin 1; 1.
DR InterPro; IPR007243; Atg6/Beclin.
DR InterPro; IPR038274; Atg6/Beclin_C_sf.
DR InterPro; IPR041691; Atg6/beclin_CC.
DR InterPro; IPR040455; Atg6_BARA.
DR PANTHER; PTHR12768; BECLIN 1; 1.
DR PANTHER; PTHR12768:SF4; BECLIN-1; 1.
DR Pfam; PF04111; APG6; 1.
DR Pfam; PF17675; APG6_N; 1.
PE 3: Inferred from homology;
FT DOMAIN 180..314
FT /note="Atg6/beclin coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF17675"
FT DOMAIN 317..535
FT /note="Atg6 BARA"
FT /evidence="ECO:0000259|Pfam:PF04111"
FT REGION 93..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..127
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..237
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 557 AA; 63163 MW; D3BAFD719D76EC0F CRC64;
MKCQTCHLPL QLDPSLEGLS LTQRNLLLSN NSIITATNEN VISNKGIEAA DNCGPQIPKE
RLRRLGEIQN IKDLNLIDDK LITDSFVFLN HDDDDNANIT SNSREDQRYG NANGNDNKKA
NSDTSDGTST FRDHDEEEQE ATDEDENQQI QLNSKTLSTQ VNAMTNVFNI LSSQTNIDFP
ICQDCCNILI NRLKSEYDDA IKERDTYAQF LSKLESQNKE ISESNKEKQY SHNLSEKESL
KKEEERLLDQ LLRLEMTDDD LDGELVRLQE KKVQLENEKL QKLSDQNLMD LNNIQFNKNL
QSLKLQYELS LNQLDKLRKI NIFNATFKIS HSGPFATING LRLGSIPESV VPWKEINAAL
GQLILLLATI NKNLKINLVD YELQPMGSFS KIKKRMVNSV EYNNSTTNAP GDWLILPVYY
DENFNLGRIF RKETKFDKSL ETTLEIISEI TRQLSTIASS YSSQTLATSQ DESSMNNAND
VENSTSILEL PYIMNKDKIN GLSVKLHGSS PNLEWTTAMK FLLTNVKWLL AFSSNLLSKS
ITLSPTVNHN DKTISGN
//
