ID A7EM75_SCLS1 Unreviewed; 1171 AA.
AC A7EM75;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 24-JAN-2024, entry version 85.
DE RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN ORFNames=SS1G_06422 {ECO:0000313|EMBL:EDO03941.1};
OS Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS (Whetzelinia sclerotiorum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Sclerotinia.
OX NCBI_TaxID=665079 {ECO:0000313|EMBL:EDO03941.1, ECO:0000313|Proteomes:UP000001312};
RN [1] {ECO:0000313|Proteomes:UP000001312}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18683 / 1980 / Ss-1 {ECO:0000313|Proteomes:UP000001312};
RX PubMed=21876677; DOI=.1371/journal.pgen.1002230;
RA Amselem J., Cuomo C.A., van Kan J.A., Viaud M., Benito E.P., Couloux A.,
RA Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.M.,
RA Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA Grossetete S., Guldener U., Henrissat B., Howlett B.J., Kodira C.,
RA Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA Zeng Q., Rollins J.A., Lebrun M.H., Dickman M.;
RT "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT sclerotiorum and Botrytis cinerea.";
RL PLoS Genet. 7:E1002230-E1002230(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR005719}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
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DR EMBL; CH476628; EDO03941.1; -; Genomic_DNA.
DR RefSeq; XP_001592183.1; XM_001592133.1.
DR AlphaFoldDB; A7EM75; -.
DR STRING; 665079.A7EM75; -.
DR GeneID; 5488643; -.
DR KEGG; ssl:SS1G_06422; -.
DR VEuPathDB; FungiDB:sscle_13g092680; -.
DR InParanoid; A7EM75; -.
DR OMA; DQHQSMR; -.
DR OrthoDB; 231904at2759; -.
DR Proteomes; UP000001312; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0061775; F:cohesin loader activity; IBA:GO_Central.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007064; P:mitotic sister chromatid cohesion; IBA:GO_Central.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 2.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|PIRNR:PIRNR005719};
KW Reference proteome {ECO:0000313|Proteomes:UP000001312}.
FT DOMAIN 466..578
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT REGION 1091..1118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 131..165
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 204..238
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 364..447
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 617..644
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 687..758
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 807..851
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 903..961
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1171 AA; 133707 MW; 0482CCDFCA1D8849 CRC64;
MGREERQALL HEGSGSAVMS AYVEIIFDNS DGRFPTGKNE LYLRRTIGLK KDEYSLDKKN
ATKTDVLNLL ETAGFSRSNP YYIVPQGRVT ALTNMKDGER LNLLKEVAGT QVYEQRRTES
LKIMTDTNNK RAKIDELLDY IKERLAELEE EKEELRGYQE KDKDRRCLQY AFFHQEQVAI
AEKLEEIDEF RQGGGNGDEN RDAFLEGEKA IAELDAQIKQ LNRQIELLGV DKRQLEEDRR
DTAKTRAKIE LHVKTLTVNQ SSTEQARVRH QQELSSVKKE IASKEAELAQ LLPDFESRKA
SEGEIRRSLD EAEAGRSRLY AKQARSNQYK TKAERDQFLR KEIEDLNSSI GSQKANRIDG
DEEVKHVQSE IRNLETEISG LQERLDGWSG NRIALAEEVS TAKDALEKLQ DERKLLRRED
EKLHSVIEDA RKEVSIAESE LSRTMDSATS RGLATVRRLK QQHKIQGAYG TLAELLEVEE
LYRVAVEQTA GSSLFNYVVD NEETATQLIN ALNADKGGRV TFVPLSQLRT KPATLPNASD
AIPMLSKIRY DKKYQPAFEQ VFGKTIVCPN LTIAAQYARS HGCNAITPDG DTTNKKGALT
GGYLNPKESR LQAVRALNKW RDEYETLRVR QDEIRKELEQ KDQEITAAFT EEQKASQKMN
QFVDSLDPLK SGLRSRQSHL ERQKIQLEKL LQNQADVIKL LQEHNRKISD YEAEIASDFK
KALTANEERQ LEQLNASVQD LQKQWNEHSR NRRELESRKQ LIEVDLRENL RLKLDQLNNQ
EMDLASGSGT GNLKESQREL KRIIKASAVV ETKLQENENS LEEAESNIIN LQQEKSQKED
EQQKIAVLIE KHQKKMERSI ARKAILTTSA SDCAKNIRDL GVLPDEAFEK YKDYDPKSIQ
SRLKKVQEAL KKYKHVNKKA FEQYNQFTTQ RDSLTKRRKE LDDSQASIQE LVEVLDQRKD
EAIERTFKQV SKEFAQIFER LVPAGRGRLV IQRKADRRAR EEEDSDEEAR DSVENYVGVG
ISVSFNSKHD DQQRIQQLSG GQKSLCALAL VFAIQQCDPA PFYLFDEIDA NLDAQYRTAV
AQMLKEISAK QSQAFQSQDN SDEESDNDED DEGGSKKQKV MGGQFICTTF RPEMVLVANK
CYGVTFHNKT SNIGVVGKED ALSFVDGEAP K
//
