ID A7IKQ4_XANP2 Unreviewed; 324 AA.
AC A7IKQ4;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=TRAP dicarboxylate transporter, DctP subunit {ECO:0000313|EMBL:ABS68597.1};
DE Flags: Precursor;
GN OrderedLocusNames=Xaut_3368 {ECO:0000313|EMBL:ABS68597.1};
OS Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Xanthobacteraceae; Xanthobacter.
OX NCBI_TaxID=78245 {ECO:0000313|EMBL:ABS68597.1, ECO:0000313|Proteomes:UP000002417};
RN [1] {ECO:0000313|EMBL:ABS68597.1, ECO:0000313|Proteomes:UP000002417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1158 / Py2 {ECO:0000313|Proteomes:UP000002417};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D.,
RA Detter J.C., Han C., Tapia R., Brainard J., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P.;
RT "Complete sequence of chromosome of Xanthobacter autotrophicus Py2.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0007829|PDB:4OVR}
RP X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) OF 26-324 IN COMPLEX WITH
RP GALACTURONATE.
RX PubMed=25540822; DOI=10.1021/bi501388y;
RA Vetting M.W., Al-Obaidi N., Zhao S., San Francisco B., Kim J.,
RA Wichelecki D.J., Bouvier J.T., Solbiati J.O., Vu H., Zhang X.,
RA Rodionov D.A., Love J.D., Hillerich B.S., Seidel R.D., Quinn R.J.,
RA Osterman A.L., Cronan J.E., Jacobson M.P., Gerlt J.A., Almo S.C.;
RT "Experimental strategies for functional annotation and metabolism
RT discovery: targeted screening of solute binding proteins and unbiased
RT panning of metabolomes.";
RL Biochemistry 54:909-931(2015).
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 7 family.
CC {ECO:0000256|ARBA:ARBA00009023}.
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DR EMBL; CP000781; ABS68597.1; -; Genomic_DNA.
DR PDB; 4OVR; X-ray; 1.65 A; A/B=26-324.
DR PDBsum; 4OVR; -.
DR AlphaFoldDB; A7IKQ4; -.
DR SMR; A7IKQ4; -.
DR STRING; 78245.Xaut_3368; -.
DR KEGG; xau:Xaut_3368; -.
DR eggNOG; COG1638; Bacteria.
DR HOGENOM; CLU_036176_4_0_5; -.
DR OrthoDB; 9803763at2; -.
DR PhylomeDB; A7IKQ4; -.
DR Proteomes; UP000002417; Chromosome.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd13671; PBP2_TRAP_SBP_like_3; 1.
DR Gene3D; 3.40.190.170; Bacterial extracellular solute-binding protein, family 7; 1.
DR InterPro; IPR018389; DctP_fam.
DR InterPro; IPR004682; TRAP_DctP.
DR InterPro; IPR038404; TRAP_DctP_sf.
DR NCBIfam; TIGR00787; dctP; 1.
DR NCBIfam; NF037995; TRAP_S1; 1.
DR PANTHER; PTHR33376; -; 1.
DR PANTHER; PTHR33376:SF2; 2,3-DIKETO-L-GULONATE-BINDING PERIPLASMIC PROTEIN YIAO; 1.
DR Pfam; PF03480; DctP; 1.
DR PIRSF; PIRSF006470; DctB; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:4OVR};
KW Reference proteome {ECO:0000313|Proteomes:UP000002417};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..324
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002708740"
FT BINDING 34
FT /ligand="beta-D-galacturonate"
FT /ligand_id="ChEBI:CHEBI:85312"
FT /evidence="ECO:0007829|PDB:4OVR"
FT BINDING 72
FT /ligand="beta-D-galacturonate"
FT /ligand_id="ChEBI:CHEBI:85312"
FT /evidence="ECO:0007829|PDB:4OVR"
FT BINDING 88
FT /ligand="beta-D-galacturonate"
FT /ligand_id="ChEBI:CHEBI:85312"
FT /evidence="ECO:0007829|PDB:4OVR"
FT BINDING 148
FT /ligand="beta-D-galacturonate"
FT /ligand_id="ChEBI:CHEBI:85312"
FT /evidence="ECO:0007829|PDB:4OVR"
FT BINDING 168
FT /ligand="beta-D-galacturonate"
FT /ligand_id="ChEBI:CHEBI:85312"
FT /evidence="ECO:0007829|PDB:4OVR"
FT BINDING 208
FT /ligand="beta-D-galacturonate"
FT /ligand_id="ChEBI:CHEBI:85312"
FT /evidence="ECO:0007829|PDB:4OVR"
FT BINDING 209
FT /ligand="beta-D-galacturonate"
FT /ligand_id="ChEBI:CHEBI:85312"
FT /evidence="ECO:0007829|PDB:4OVR"
FT BINDING 235
FT /ligand="beta-D-galacturonate"
FT /ligand_id="ChEBI:CHEBI:85312"
FT /evidence="ECO:0007829|PDB:4OVR"
SQ SEQUENCE 324 AA; 35649 MW; 7AD42E7589540DC3 CRC64;
MKGLALYVAA AMTSVIALTP LAAQARQYRS ADVQPADYPT VKAVQSMSDE LNKETNGKIS
IKVFPNSQLG SEKDTIEQVK LGALDFIRIN SGTLNTVCPA MTVPVLPFLF RDKAHMRAVL
DGPIGDEILA DCASHGLVGL AFYDSGARSF YATTPIRKLE DLKGKKIRVQ QSDIWVSMMK
LLGANATPMP AGEVFTGLKS GLIDGAENNW PSYDNFHHYE AAKNYSLSEH SMAPEVLLIS
KRVFDSFTPE EQVQVRKAAK NSVGYMRQLW DAMEISSREK VEKAGVEVIT IDKAPFQAAV
QPLYDQFVTD PKLKDMITRI KAAQ
//
