ID A7KX08_9BURK Unreviewed; 370 AA.
AC A7KX08;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Chloromuconate cycloisomerase {ECO:0000313|EMBL:ABS81347.1};
GN Name=clcB {ECO:0000313|EMBL:ABS81347.1};
OS Pandoraea pnomenusa.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Pandoraea.
OX NCBI_TaxID=93220 {ECO:0000313|EMBL:ABS81347.1};
RN [1] {ECO:0000313|EMBL:ABS81347.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MCB032 {ECO:0000313|EMBL:ABS81347.1};
RX PubMed=19365620; DOI=10.1007/s00203-009-0476-9;
RA Jiang X.W., Liu H., Xu Y., Wang S.J., Leak D.J., Zhou N.Y.;
RT "Genetic and biochemical analyses of chlorobenzene degradation gene
RT clusters in Pandoraea sp. strain MCB032.";
RL Arch. Microbiol. 191:485-492(2009).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- PATHWAY: Aromatic compound metabolism. {ECO:0000256|ARBA:ARBA00005211}.
CC -!- SIMILARITY: Belongs to the mandelate racemase/muconate lactonizing
CC enzyme family. {ECO:0000256|ARBA:ARBA00008031}.
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DR EMBL; EF600715; ABS81347.1; -; Genomic_DNA.
DR RefSeq; WP_063599758.1; NZ_CP015373.1.
DR AlphaFoldDB; A7KX08; -.
DR UniPathway; UPA00083; -.
DR GO; GO:0018850; F:chloromuconate cycloisomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0018849; F:muconate cycloisomerase activity; IEA:InterPro.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR CDD; cd03318; MLE; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR013370; Chloromuconate_cycloisomerase.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR NCBIfam; TIGR02534; mucon_cyclo; 1.
DR PANTHER; PTHR48073:SF2; O-SUCCINYLBENZOATE SYNTHASE; 1.
DR PANTHER; PTHR48073; O-SUCCINYLBENZOATE SYNTHASE-RELATED; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDG01258; (chloro)muconate_cycloisomeras; 1.
DR SFLD; SFLDS00001; Enolase; 1.
DR SFLD; SFLDF00009; o-succinylbenzoate_synthase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00908; MR_MLE_1; 1.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ABS81347.1};
KW Manganese {ECO:0000256|ARBA:ARBA00023211}.
FT DOMAIN 143..241
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 370 AA; 39803 MW; 9A686595D7B585E4 CRC64;
MKIEAIDVTL VDVPASRPIQ MSFTTVQKQS YAIVQIRAGG LVGIGEGSSV GGPTWSSECA
ETIKVIIETY LAPLLIGKDA TNLRELQHLM ERAVTGNYSA KAAIDVALHD LKARSLNLPL
SDLIGGAIQQ GIPIAWTLAS GDTQRDIAIA EEMIERRRHN RFKIKLGVRS PADDLRHIER
IIERVGDRAA VRVDINQAWD ENTASVWIPR LEAAGVELVE QPVARSNFDA LRRLSADNGV
AILADESLSS LASAFELARH HCVDAFSLKL CNMGGVANTL KVAAIAEASG IASYGGTMLD
SSIGTAAALH VYATLPTMPF GCELLGPWVL ADTLTQTQLE IKDFEIRLPS GPGLGVDIDP
DKLRHFTRAG
//
