ID A7LCE1_9FUSO Unreviewed; 336 AA.
AC A7LCE1;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 13-SEP-2023, entry version 50.
DE SubName: Full=Electron transfer flavoprotein alpha subunit {ECO:0000313|EMBL:ABS29302.1};
DE SubName: Full=Electron transfer flavoprotein subunit alpha/FixB family protein {ECO:0000313|EMBL:AYZ72804.1};
DE Flags: Fragment;
GN ORFNames=EGX98_01255 {ECO:0000313|EMBL:AYZ72804.1};
OS Fusobacterium necrophorum.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=859 {ECO:0000313|EMBL:ABS29302.1};
RN [1] {ECO:0000313|EMBL:ABS29302.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FN {ECO:0000313|EMBL:ABS29302.1};
RA Miao L.G., Wang Z.G., liu Y.H., Yang F.H., Li Y.;
RT "Selecting of Fusobacterium necrophorum genes.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AYZ72804.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FDAARGOS_565 {ECO:0000313|EMBL:AYZ72804.1};
RA Minogue T., Wolcott M., Wasieloski L., Aguilar W., Moore D., Jaissle J.,
RA Tallon L.J., Sadzewicz L., Zhao X., Vavikolanu K., Mehta A.,
RA Aluvathingal J., Nadendla S., Yan Y., Sichtig H.;
RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
RT Supporting development and validation of Infectious Disease Dx tests.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000278951}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FDAARGOS_565 {ECO:0000313|Proteomes:UP000278951};
RA Minogue T., Wolcott M., Wasieloski L., Aguilar W., Moore D., Jaissle J.,
RA Tallon L., Sadzewicz L., Zhao X., Vavikolanu K., Mehta A., Aluvathingal J.,
RA Nadendla S., Yan Y., Sichtig H.;
RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
RT Supporting development and validation of Infectious Disease Dx tests.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000089-1};
CC Note=Binds 1 FAD per dimer. {ECO:0000256|PIRSR:PIRSR000089-1};
CC -!- SIMILARITY: Belongs to the ETF alpha-subunit/FixB family.
CC {ECO:0000256|ARBA:ARBA00005817}.
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DR EMBL; EU003587; ABS29302.1; -; Genomic_DNA.
DR EMBL; CP033837; AYZ72804.1; -; Genomic_DNA.
DR RefSeq; WP_035901836.1; NZ_JADRHJ010000045.1.
DR AlphaFoldDB; A7LCE1; -.
DR eggNOG; COG2025; Bacteria.
DR Proteomes; UP000278951; Chromosome.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd01715; ETF_alpha; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR014730; ETF_a/b_N.
DR InterPro; IPR001308; ETF_a/FixB.
DR InterPro; IPR033947; ETF_alpha_N.
DR InterPro; IPR014731; ETF_asu_C.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR43153; ELECTRON TRANSFER FLAVOPROTEIN ALPHA; 1.
DR PANTHER; PTHR43153:SF1; ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF01012; ETF; 1.
DR Pfam; PF00766; ETF_alpha; 1.
DR PIRSF; PIRSF000089; Electra_flavoP_a; 1.
DR SMART; SM00893; ETF; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000089-1};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000089-1}.
FT DOMAIN 9..198
FT /note="Electron transfer flavoprotein alpha/beta-subunit N-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00893"
FT BINDING 222
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 247..248
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 261..265
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 278..285
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 299
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT NON_TER 336
FT /evidence="ECO:0000313|EMBL:ABS29302.1"
SQ SEQUENCE 336 AA; 36526 MW; 6CEC3BF42191DD20 CRC64;
MNLSDYKGIL VFAEQRDGKV QNVALELLGK ARELAEDIDT KTVSAVLIGE NVKGLADELI
QYGADIVYVV EGADYKIYDT EKYAQVFKSV IDSKKPEIVL FGATTIGRDL APRVSSRMVT
GLTADCTKLE IAEDKSLWMT RPAFGGNLMA TIVCPDHRPQ MSTVRPGVMK KMPKDTARKG
EIVDYPVTLD LSKVKVEVLD VVKEEGNKVD ISEAKILVSG GRGVGHKSNF QELEELAAEI
GGVVSASRAQ VDAGNMPHDR QVGQTGKTVR PSIYFACGIS GAIQHVAGME ESEFIIAINK
DRYAPIFSVA DLGIVGDVHK VLPLLTEEIK KFKATK
//
