ID A7LJS6_XYLFS Unreviewed; 141 AA.
AC A7LJS6;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=DNA topoisomerase (ATP-hydrolyzing) {ECO:0000256|ARBA:ARBA00012895};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
OS Xylella fastidiosa.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xylella.
OX NCBI_TaxID=2371 {ECO:0000313|EMBL:ABS72206.1};
RN [1] {ECO:0000313|EMBL:ABS72206.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BLA TEX 001 {ECO:0000313|EMBL:ABS72209.1}, GIL BEC 631
RC {ECO:0000313|EMBL:ABS72206.1}, LLA FAL 634
RC {ECO:0000313|EMBL:ABS72210.1}, PD {ECO:0000313|EMBL:ABS72212.1}, TRA
RC FLA 300 {ECO:0000313|EMBL:ABS72208.1}, VAL VAL 036
RC {ECO:0000313|EMBL:ABS72207.1}, and VAL VAL 048
RC {ECO:0000313|EMBL:ABS72211.1};
RA Bextine B., Morano L., Gunawan S.;
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABS72206.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BLA TEX 001 {ECO:0000313|EMBL:ABS72209.1}, GIL BEC 631
RC {ECO:0000313|EMBL:ABS72206.1}, LLA FAL 634
RC {ECO:0000313|EMBL:ABS72210.1}, PD {ECO:0000313|EMBL:ABS72212.1}, TRA
RC FLA 300 {ECO:0000313|EMBL:ABS72208.1}, VAL VAL 036
RC {ECO:0000313|EMBL:ABS72207.1}, and VAL VAL 048
RC {ECO:0000313|EMBL:ABS72211.1};
RX PubMed=18172717; DOI=10.1007/s00284-007-9088-2;
RA Morano L.D., Bextine B.R., Garcia D.A., Maddox S.V., Gunawan S.,
RA Vitovsky N.J., Black M.C.;
RT "Initial genetic analysis of Xylella fastidiosa in Texas.";
RL Curr. Microbiol. 56:346-351(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; EU026146; ABS72206.1; -; Genomic_DNA.
DR EMBL; EU026147; ABS72207.1; -; Genomic_DNA.
DR EMBL; EU026148; ABS72208.1; -; Genomic_DNA.
DR EMBL; EU026149; ABS72209.1; -; Genomic_DNA.
DR EMBL; EU026150; ABS72210.1; -; Genomic_DNA.
DR EMBL; EU026151; ABS72211.1; -; Genomic_DNA.
DR EMBL; EU026152; ABS72212.1; -; Genomic_DNA.
DR AlphaFoldDB; A7LJS6; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 66..141
FT /note="DNA topoisomerase type IIA subunit B"
FT /evidence="ECO:0000259|Pfam:PF00204"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABS72206.1"
FT NON_TER 141
FT /evidence="ECO:0000313|EMBL:ABS72206.1"
SQ SEQUENCE 141 AA; 15912 MW; 4F358B6B704797FE CRC64;
SLEVSAKRGT TLRFKPAKEI FSDVEFHYEN LAKRLRELSF LNSGLKVSLI DERGEGRRDD
FHYEGGIRSF VEHLAQLKTP LHPNVISVTG EHNGIVVDAA LQWTDAYQET MYCFTNNIPQ
KDGGTHLAGF RAALTRTLGN Y
//
