ID A7LYH6_BACO1 Unreviewed; 499 AA.
AC A7LYH6;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE SubName: Full=Succinate CoA transferase {ECO:0000313|EMBL:EDO11683.1};
DE EC=2.8.3.- {ECO:0000313|EMBL:EDO11683.1};
GN ORFNames=BACOVA_02893 {ECO:0000313|EMBL:EDO11683.1};
OS Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 /
OS CCUG 4943 / NCTC 11153).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=411476 {ECO:0000313|EMBL:EDO11683.1, ECO:0000313|Proteomes:UP000005475};
RN [1] {ECO:0000313|EMBL:EDO11683.1, ECO:0000313|Proteomes:UP000005475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC
RC 11153 {ECO:0000313|Proteomes:UP000005475};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDO11683.1, ECO:0000313|Proteomes:UP000005475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC
RC 11153 {ECO:0000313|Proteomes:UP000005475};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Bacteroides ovatus (ATCC 8483).";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO11683.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAXF02000049; EDO11683.1; -; Genomic_DNA.
DR RefSeq; WP_004298843.1; NZ_DS264579.1.
DR AlphaFoldDB; A7LYH6; -.
DR GeneID; 29453795; -.
DR eggNOG; COG0427; Bacteria.
DR HOGENOM; CLU_019748_3_0_10; -.
DR Proteomes; UP000005475; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Transferase {ECO:0000313|EMBL:EDO11683.1}.
FT DOMAIN 5..211
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 317..458
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 284
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 354
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 374
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 378
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 398
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 499 AA; 54021 MW; DE8E83845A7983E6 CRC64;
MSLNRISAAE AASLIKHGYN IGLSGFTPAG TAKAVTAELA KIAEAEHAKG NPFQVGIFTG
ASTGESCDGV LSRAKAIRYR APYTTNSDFR KAVNNGEIAY NDIHLSQMAQ EVRYGFMGKV
NVAIIEACEV TPDGKIYLTA AGGIAPTICR LADQIIVELN SAHSKSCMGL HDVYEPLDPP
YRREIPIYKP SDRIGLPYVQ VDPKKIIGVV ETNWPDEARS FAAADPLTDK IGQNVADFLA
ADMKRGIIPS TFLPLQSGVG NIANAVLGAL GRDKTIPPFE MYTEVIQNSV IGLIREGRIK
FGSACSLTVT NDCLEGIYND MDFFRDKLVL RPSEISNSPE IVRRLGIISI NTAIEVDLYG
NVNSTHIGGT KMMNGIGGSG DFTRNAYISI FTCPSVAKEG KISAIVPMVS HHDHTEHDVN
IVITEQGVAD LRGKSPKERA QAIIENCAHP DYKELLWDYL KLAGNRAQTP HAIQAALGMH
AELAKSGDMK NTNWAEYAK
//
