ID A7MB96_BOVIN Unreviewed; 654 AA.
AC A7MB96;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 22-FEB-2023, entry version 90.
DE SubName: Full=ARHGAP24 protein {ECO:0000313|EMBL:AAI51438.1};
GN Name=ARHGAP24 {ECO:0000313|EMBL:AAI51438.1};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAI51438.1};
RN [1] {ECO:0000313|EMBL:AAI51438.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hereford {ECO:0000313|EMBL:AAI51438.1};
RC TISSUE=Fetal pons {ECO:0000313|EMBL:AAI51438.1};
RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y.,
RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C.,
RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J.,
RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J.,
RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., Siddiqui A.,
RA Holt R., Jones S.J., Marra M.A.;
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; BC151437; AAI51438.1; -; mRNA.
DR RefSeq; NP_001095704.1; NM_001102234.1.
DR AlphaFoldDB; A7MB96; -.
DR GeneID; 539902; -.
DR KEGG; bta:539902; -.
DR CTD; 83478; -.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04390; RhoGAP_ARHGAP22_24_25; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228:SF19; RHO GTPASE-ACTIVATING PROTEIN 24; 1.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 1..30
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 40..234
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 264..337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 349..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 558..634
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 264..278
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..523
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 654 AA; 73309 MW; 54977640C1CAF905 CRC64;
MTANHESYLL MASTQNDMED WVKSIRRVIW GPFGGGIFGQ KLEDTVRYEK RYGNRLAPML
VEQCVDFIRQ RGLKEEGLFR LPGQTNLVKE LQDAFDCGEK PSFDSNTDVH TVASLLKLYL
RELPEPVIPY AKYEDFLSCA KLLSKEEEAG VKELAKQVKS LPVVNYNLLK YICRFLDEVQ
SYSGINKMSV QNLATVFGPN ILRPKVEDPL TIMEGTVVVQ QLMSVMIGKH DRLFPKDAEL
QSKPQDGVSN NNNDLQKKAL MGQLQNKENN NTNDSPVRRC SWDKPESPQR SSMDNGSPTA
LPGSKTNSPR NSIHKLDVSR SPPLMVKKNP AFNKGSGIVT NGSFSSSNAE ALEKAQTTPN
GSLQARRTSS LKGSGTKMGT HSVQNGTVRM GILNSDTLGN PGNGRSMSWL PNGYVTLRDN
KQKEQAGESG QHNRLSTYDN VHQQFSAMSL DDKQSVDSAT WSTSSCEISL PENSTSCRSS
TTTCPEQDFY GGNFEDPVLD GPPQDDLSHP ADYENKSDRR SVGGRSSRAT SSSDNSETFV
SNNTSNHSAL HSLVSSLKQE MTKQKIEYES RIKSLEQRNL TLETEMMSLH DELDQERKKF
TMIEIKMRNA ERAKEDAEKR NDMLQKEMEQ FFSTFGELTV EPRRTERGNT IWIQ
//
