ID UBIA_VIBHB Reviewed; 284 AA.
AC A7N0X0;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 1.
DT 01-MAY-2013, entry version 45.
DE RecName: Full=4-hydroxybenzoate octaprenyltransferase;
DE EC=2.5.1.-;
DE AltName: Full=4-HB polyprenyltransferase;
GN Name=ubiA; OrderedLocusNames=VIBHAR_00272;
OS Vibrio harveyi (strain ATCC BAA-1116 / BB120).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC Vibrionaceae; Vibrio.
OX NCBI_TaxID=338187;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1116 / BB120;
RG The Vibrio harveyi Genome Sequencing Project;
RA Bassler B., Clifton S.W., Fulton L., Delehaunty K., Fronick C.,
RA Harrison M., Markivic C., Fulton R., Tin-Wollam A.-M., Shah N.,
RA Pepin K., Nash W., Thiruvilangam P., Bhonagiri V., Waters C., Tu K.C.,
RA Irgon J., Wilson R.K.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesis of 3-octaprenyl-4-hydroxybenzoate (By
CC similarity).
CC -!- CATALYTIC ACTIVITY: 4-hydroxybenzoate + farnesylfarnesylgeraniol =
CC 3-octaprenyl-4-hydroxybenzoate.
CC -!- COFACTOR: Magnesium (By similarity).
CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC protein (By similarity).
CC -!- SIMILARITY: Belongs to the UbiA prenyltransferase family.
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DR EMBL; CP000789; ABU69300.1; -; Genomic_DNA.
DR RefSeq; YP_001443527.1; NC_009783.1.
DR STRING; 338187.VIBHAR_00272; -.
DR EnsemblBacteria; ABU69300; ABU69300; VIBHAR_00272.
DR GeneID; 5555027; -.
DR KEGG; vha:VIBHAR_00272; -.
DR PATRIC; 20127435; VBIVibHar24526_0313.
DR eggNOG; COG0382; -.
DR HOGENOM; HOG000003696; -.
DR KO; K03179; -.
DR OMA; RITIQIC; -.
DR ProtClustDB; PRK12848; -.
DR UniPathway; UPA00232; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008412; F:4-hydroxybenzoate octaprenyltransferase activity; IEA:HAMAP.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:HAMAP.
DR HAMAP; MF_01635; UbiA; 1; -.
DR InterPro; IPR006370; HB_polyprenyl-transferase.
DR InterPro; IPR000537; UbiA_prenyltransferase.
DR Pfam; PF01040; UbiA; 1.
DR TIGRFAMs; TIGR01474; ubiA_proteo; 1.
DR PROSITE; PS00943; UBIA; FALSE_NEG.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Complete proteome; Magnesium;
KW Membrane; Transferase; Transmembrane; Transmembrane helix;
KW Ubiquinone biosynthesis.
FT CHAIN 1 284 4-hydroxybenzoate octaprenyltransferase.
FT /FTId=PRO_1000069836.
FT TRANSMEM 20 39 Helical; (Potential).
FT TRANSMEM 44 66 Helical; (Potential).
FT TRANSMEM 93 113 Helical; (Potential).
FT TRANSMEM 114 130 Helical; (Potential).
FT TRANSMEM 136 156 Helical; (Potential).
FT TRANSMEM 159 179 Helical; (Potential).
FT TRANSMEM 209 229 Helical; (Potential).
FT TRANSMEM 231 248 Helical; (Potential).
FT TRANSMEM 264 284 Helical; (Potential).
SQ SEQUENCE 284 AA; 32329 MW; F35A92CB72D1DE36 CRC64;
MSAEKAKAYW QLMRMDRPIG SLLLLWPTVW ALVIAAQGMP SWNVLIVFVL GVFLMRSAGC
VINDFADRKV DGHVKRTKQR PLPSGKVTSK EAIGLFLVLG ISSFLLVLTM NPLTIKLSFA
GIFLAFIYPF MKRYTYLPQL FLGLAFSWAI PMAWAAQTGE LPWIVWFVFV INALWTIAYD
TQYAMVDRDD DLKIGIKSTA ILFGRHDKLV IGVLQLVTLA MLVLLGQHYE LGQSYYWTIL
VAASLFVYQQ HLIRHRERDL CFKAFLNNNY VGIVIVIGLL IAFW
//
