ID A7NRY1_ROSCS Unreviewed; 579 AA.
AC A7NRY1;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Rcas_4301 {ECO:0000313|EMBL:ABU60327.1};
OS Roseiflexus castenholzii (strain DSM 13941 / HLO8).
OC Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Roseiflexineae;
OC Roseiflexaceae; Roseiflexus.
OX NCBI_TaxID=383372 {ECO:0000313|EMBL:ABU60327.1, ECO:0000313|Proteomes:UP000000263};
RN [1] {ECO:0000313|EMBL:ABU60327.1, ECO:0000313|Proteomes:UP000000263}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13941 / HLO8 {ECO:0000313|Proteomes:UP000000263};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Detter J.C.,
RA Han C., Tapia R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Bryant D.A., Hanada S., Tsukatani Y., Richardson P.;
RT "Complete sequence of Roseiflexus castenholzii DSM 13941.";
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP000804; ABU60327.1; -; Genomic_DNA.
DR RefSeq; WP_012122748.1; NC_009767.1.
DR AlphaFoldDB; A7NRY1; -.
DR STRING; 383372.Rcas_4301; -.
DR KEGG; rca:Rcas_4301; -.
DR eggNOG; COG2205; Bacteria.
DR eggNOG; COG3850; Bacteria.
DR HOGENOM; CLU_000445_89_2_0; -.
DR OrthoDB; 9790669at2; -.
DR Proteomes; UP000000263; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR024478; HlyB_4HB_MCP.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF12729; 4HB_MCP_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABU60327.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000000263};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 210..262
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 315..538
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 254..308
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 579 AA; 64215 MW; C3963AF585530A5B CRC64;
MNLSIRTKLL AALGVDLILM LVLGSFALHQ MSIMNQKADF VVNQTILSID LVNAMNDVLL
NYRTRQMEYI LNAAPADKQR IEKELLDLET RMDGIFRNYS ANYQPDATER LIFEQTQQDW
QRYVFLTHTQ FLPANRNSNT GNVHPSFGRL SPLYGSLQTN MQKIRAQSQA RAEAARASVE
TAYSTSRFVI VSETILTVFV SAVIGLTLSG NIARRIRTLR DATIAVSGGD LSRQVSLRGG
DELVLLANNF NLMVASLRQQ RMLLEERNAE LSASLETQQR LMEDLVQRKQ AEEAAHRAQA
AAEAASHAKS MFLATMSHEL RTPLNAILGY VQLLHLEAQI HGRSEMLPDL ERIRSAGKHL
LTIISNILDF SKIEQGRMNV EIDTFNVSVI AHEMISIIEP LARNRNNTLT LTCPPDIGMM
QSDAGKVRQI LFNLLSNAVK FTDNGTVALT IERECCSDGD WVRFSVADTG IGMSPEQLTR
LFQPFTQVHQ SHSSHAHRGT GLGLALSQQL CRLLGGDISV TSEVGRGSVF TVRLPAVIST
AHTADVRLDF AQHIRSATRH DVDHATTAPS PYTTTTLSA
//
