ID A7RK68_NEMVE Unreviewed; 629 AA.
AC A7RK68;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE RecName: Full=Battenin {ECO:0008006|Google:ProtNLM};
GN ORFNames=NEMVEDRAFT_v1g238879 {ECO:0000313|EMBL:EDO48194.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO48194.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO48194.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the battenin family.
CC {ECO:0000256|ARBA:ARBA00007467}.
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DR EMBL; DS469515; EDO48194.1; -; Genomic_DNA.
DR RefSeq; XP_001640257.1; XM_001640207.1.
DR AlphaFoldDB; A7RK68; -.
DR EnsemblMetazoa; EDO48194; EDO48194; NEMVEDRAFT_v1g238879.
DR eggNOG; KOG3880; Eukaryota.
DR HOGENOM; CLU_029663_2_0_1; -.
DR InParanoid; A7RK68; -.
DR PhylomeDB; A7RK68; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005773; C:vacuole; IBA:GO_Central.
DR GO; GO:0051453; P:regulation of intracellular pH; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR003492; Battenin_disease_Cln3.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10981; BATTENIN; 1.
DR PANTHER; PTHR10981:SF0; BATTENIN; 1.
DR Pfam; PF02487; CLN3; 1.
DR PRINTS; PR01315; BATTENIN.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 181..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..523
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 570..592
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 363..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 70151 MW; 223B6276D39D3DAC CRC64;
MEPLVSRLPW VAEAEWSLWS PSYPGLQRLN GASGLQATLG CRGWMEPLVS RLPWVAEAEW
SLWSPGYLQA LINRLILLFL RTFKIWSRLG EAVYSRLVTN LATRPVARCG PSWEDDLIPA
LAGFLSGSLN TAKCSRYPLT IMGSLFQDRL DDNDSTKTSK KPKPKLHRGL SRLVYISEET
LSLLNISAFL VFGLLTFVNM EILFTAAEDI LSGFNIPTAS LIICFNVPLV VAKIVLPWCF
QRFPYVVHVT WLTGFMILGT LFIVFVDSMV AKMVGLGLNA MATGGSELVF LALTAYYPKV
CVSAFVCGTG IAALVAPLYY AAATTWGCLA PRAAIMLTIP WPIFFLIFYL ALDKEPIRDT
PIRATPLHRS GSTRGSMGGS TRGTMRGSTR SKVSYKTLLT KETESDSETD EPNNNTTRLS
CSNKLSVAVQ LVPLLIPLFI SFFTEYLAVT SVVTTIALPN SRLRPRDHYL YYSLFYRIGK
FMGRSYLFLL SCLPRFVDCM RDTCQYTWIF ALCNIFQLLF LLFDSWYHFV PHVEIIITVC
LGIGLFSGLI VLHSPHLVPQ LVQPNESEFA LSLLSLGNGI GGLAAAIVGL FVEPYLSAKC
QQKFDPKYCF TRFRNTTGWD NNLRCLPAS
//
