ID A7RSX6_NEMVE Unreviewed; 343 AA.
AC A7RSX6;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=Apple domain-containing protein {ECO:0000259|PROSITE:PS50948};
GN ORFNames=NEMVEDRAFT_v1g201652 {ECO:0000313|EMBL:EDO45298.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO45298.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO45298.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01172}.
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DR EMBL; DS469536; EDO45298.1; -; Genomic_DNA.
DR RefSeq; XP_001637361.1; XM_001637311.1.
DR AlphaFoldDB; A7RSX6; -.
DR STRING; 45351.A7RSX6; -.
DR EnsemblMetazoa; EDO45298; EDO45298; NEMVEDRAFT_v1g201652.
DR GeneID; 5517351; -.
DR KEGG; nve:5517351; -.
DR HOGENOM; CLU_809638_0_0_1; -.
DR InParanoid; A7RSX6; -.
DR OrthoDB; 2906629at2759; -.
DR PhylomeDB; A7RSX6; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.50.4.10; Hepatocyte Growth Factor; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003609; Pan_app.
DR InterPro; IPR001759; Pentraxin-related.
DR PANTHER; PTHR19277:SF125; B6; 1.
DR PANTHER; PTHR19277; PENTRAXIN; 1.
DR Pfam; PF00024; PAN_1; 1.
DR Pfam; PF00354; Pentaxin; 1.
DR PRINTS; PR00895; PENTAXIN.
DR SMART; SM00159; PTX; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57414; Hairpin loop containing domain-like; 1.
DR PROSITE; PS50948; PAN; 1.
DR PROSITE; PS51828; PTX_2; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..343
FT /note="Apple domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002714499"
FT DOMAIN 17..117
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
SQ SEQUENCE 343 AA; 38729 MW; B856C9152FC63AAC CRC64;
MCRTMRGHFL ALLLIWCTQQ TVLSRDGIQT EKNNMLGLFK SRKGWRLADQ EFKSVQVFSE
FECARLCVDD PRCKSANYKE AAEQSVCRLN SETSRSRKNL YIPEEGYTFL EPVKSACGSK
PCSKPFTCQE VLNSHDVLYT CNLNTDIKSN FQIRFPTRTN TDYVRLNKKV DLTKFTLTYT
VRIDDDTKDH TFISYSSSNS NGIFMLQRSR RSTPYYIKAD SKFHRVVITW DNTNGDYQFF
VDNTLVLKDT GLAKGKIVAG GTGIFVLGND QDTIGGGYVL ADALVGTITR VNLWDVVLPD
EYIEILGQGC GNEVGTVLAW TEFRKETSSY NGGALFEEPS SCS
//
