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Database: UniProt
Entry: A7RTZ8_NEMVE
LinkDB: A7RTZ8_NEMVE
Original site: A7RTZ8_NEMVE 
ID   A7RTZ8_NEMVE            Unreviewed;      1557 AA.
AC   A7RTZ8;
DT   02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   02-OCT-2007, sequence version 1.
DT   25-OCT-2017, entry version 61.
DE   SubName: Full=Predicted protein {ECO:0000313|EMBL:EDO45175.1};
DE   Flags: Fragment;
GN   ORFNames=v1g93026 {ECO:0000313|EMBL:EDO45175.1};
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351 {ECO:0000313|Proteomes:UP000001593};
RN   [1] {ECO:0000313|EMBL:EDO45175.1, ECO:0000313|Proteomes:UP000001593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J.,
RA   Salamov A., Terry A., Shapiro H., Lindquist E., Kapitonov V.V.,
RA   Jurka J., Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E.,
RA   Finnerty J.R., Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
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DR   EMBL; DS469538; EDO45175.1; -; Genomic_DNA.
DR   RefSeq; XP_001637238.1; XM_001637188.1.
DR   STRING; 45351.NEMVEDRAFT_v1g93026-PA; -.
DR   EnsemblMetazoa; EDO45175; EDO45175; NEMVEDRAFT_v1g93026.
DR   GeneID; 5517155; -.
DR   KEGG; nve:NEMVE_v1g93026; -.
DR   eggNOG; KOG2301; Eukaryota.
DR   eggNOG; ENOG410XNP6; LUCA.
DR   HOGENOM; HOG000012967; -.
DR   InParanoid; A7RTZ8; -.
DR   KO; K21863; -.
DR   OMA; MLGDSAM; -.
DR   OrthoDB; EOG091G00F9; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005261; F:cation channel activity; IBA:GO_Central.
DR   GO; GO:0006816; P:calcium ion transport; IBA:GO_Central.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:GO_Central.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028823; NALCN.
DR   PANTHER; PTHR10037:SF214; PTHR10037:SF214; 1.
DR   Pfam; PF00520; Ion_trans; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001593};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     12     30       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     42     63       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     84    102       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    150    172       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    235    256       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    268    290       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    382    402       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    414    437       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    469    489       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    532    561       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    859    876       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    922    941       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    992   1012       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1108   1128       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1179   1199       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1211   1235       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1247   1265       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1271   1288       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1300   1333       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1395   1422       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       12    300       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      374    565       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      858   1130       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1184   1430       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:EDO45175.1}.
FT   NON_TER    1557   1557       {ECO:0000313|EMBL:EDO45175.1}.
SQ   SEQUENCE   1557 AA;  177860 MW;  2A613733211FDA9D CRC64;
     ESQKLAWLKS WWFKRLIQVC SVLSLISMAM NTPETFQNIP SLFYVTLLLD IALATVFTVE
     MIAQIRKFGF IVELRAYLKR PQCIFNLSML ILIVLSIILQ LVELTGYKPD PYIIFSIPRA
     PRALIMVRVF KLFVNFRLDN EVSRRCRRQI WSVTIFFLYF MTLASIIGVQ MFGSKNYYCV
     RNTTDLSNVT YSDLLLPDAR CSISHERGYF CPNDFYCAQI NLKPFMADRR YFDHFFYSLL
     TVYTSSTQEG WVLVMYQMMN VRSEVLVVIY FVLMMFFIAW LVKNVFIAVV SETFADVRSQ
     YSKSRSSSRR RYTGLSSLVI KDQGAGWHLV SVDHEASKGH APLPIRNIVA SRYARWFIWT
     AVLVDALIQA NNGSWRRRAQ FVFTILFDIE ALIKIWCVGF RTYLNSSRMQ FFEFILAVGS
     TVFALPVLMS IDALAIFHVM RVLRLIGAVP GLQDFCLKIF GTGKNLGSVI LFTLFFVMVS
     SAISMQLFLT LKDGSDTIFG TYLQSLSSMF QIFTQEGWVE IVEKSMISAE AYGAALVAIF
     LIAYHLFSSL IIMSVFVAVI VDNLDIDEDL KIMKQRKMGE ETSVTHEKLP LRLRVYERFK
     EDPRIVKMSR MKFASDFPTP KIRESFMKRF VNTENVDDMP IDLSMSVPGD STVSSNVGSR
     RTALSLPVKL LNSSMPEMNR STRLFRKQST ISALINDSNH RRTLAQIAPS EINPRGGAKS
     AGLRMASRRI RTARTGRGAV TEADVKRAME MANRGGKNLQ SQISQDEAPV RRDWDIQSVR
     EKREQAASKR RMQEETLREN HPFFDQPLFM LPRDSWLRSF LKSVVHARYT IPPGHIERAT
     RGRLINIETI HKIIATQTYL EWTMVFLTLA SCLAMMTETP QVRTFDNIAT SAFEHIFVVG
     MSLELGIRIL ADGLVFTPKA VIQNFGGALD TMIYLISLIY ICWQPKSVPV NSGAQMLMIF
     RCLRPLRVLT LMPKMKKVIL ELVGGYKEIL KVSALQLILM FSFAIYGVQV FSGKLGRCSD
     PSITVKSDCK GLFYVQLADP REVTTLSGEP PSMLVPRVWK NPRNFSFDDV LQAFLALFEA
     LSLEGWLEIR DVIDYAVGSE YGFYVHTYVL LGSMIGLTLF VGVVVTNFNQ HKGIALLTVD
     QRRWQDLKKR LRLAQPLHLP PRPDDNGIRK TLYDLVQSVI YRRVVAVVVL VECGTLAVGQ
     WTTVDAPVRE VITSTAAVCT LLFVIDTILK VIAYTGPGYW HSQRNRFDVF LTSLGLIWVV
     LNFSLKGNEK AYTVATIFGV VIIIFRFLTL SGKHDTLKML MLTVVMSLVK SFFTIAVLVI
     LMMCYSLMGV ILFGTVKYGE AVNRYANFGT SFNAMILLFR VTTGEDWNKI MHDCMVGEPY
     CTPAENFWLS DCGNYAASLI FFMSFYIVVS FILLNVFVAV IIENFSLFYA SDEDSLLSNT
     DLRDFQMAWN LVDKGRKGVM SVPQAKLFMR VYIFFKQNNF LKGRLDMDNR TVPFRHMCCE
     IEKLRNGGDV SFHDVLGIIA YRSVDISRSL QLEELLEREE LEYTIEQEVA IQTIRDW
//
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