ID A7SKD9_NEMVE Unreviewed; 308 AA.
AC A7SKD9;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=WD repeat domain-containing protein 83 {ECO:0000256|ARBA:ARBA00040453};
DE AltName: Full=Mitogen-activated protein kinase organizer 1 {ECO:0000256|ARBA:ARBA00042222};
GN ORFNames=NEMVEDRAFT_v1g245850 {ECO:0000313|EMBL:EDO35821.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO35821.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO35821.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the WD repeat MORG1 family.
CC {ECO:0000256|ARBA:ARBA00038145}.
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DR EMBL; DS469686; EDO35821.1; -; Genomic_DNA.
DR RefSeq; XP_001627884.1; XM_001627834.1.
DR AlphaFoldDB; A7SKD9; -.
DR STRING; 45351.A7SKD9; -.
DR EnsemblMetazoa; EDO35821; EDO35821; NEMVEDRAFT_v1g245850.
DR GeneID; 5507240; -.
DR KEGG; nve:5507240; -.
DR eggNOG; KOG0316; Eukaryota.
DR HOGENOM; CLU_000288_57_1_1; -.
DR InParanoid; A7SKD9; -.
DR OMA; MCWDIRT; -.
DR OrthoDB; 24036at2759; -.
DR PhylomeDB; A7SKD9; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22842:SF3; WD REPEAT DOMAIN-CONTAINING PROTEIN 83; 1.
DR PANTHER; PTHR22842; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 15..56
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 57..98
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 99..141
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 245..267
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 269..300
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 308 AA; 34031 MW; 9A297E251AB90120 CRC64;
MSADAKLPSK QTGLLQGHQG AVRAVRFNSD GNYCLTCGSD KILALWNPHK ATRLKTYSGH
GYEVLDAVAA GDSSRIASCS ADRTVVLWDV STGQVIRRYR GHTSRVNCVK FNQPDSTVII
SGSYDSTIRC WDCRSRSQEP VQVIDDAKDS VTSVHVSSHE ILSGSVDCKV RNYDIRMGTM
HADCIGEPVT SVTFTQDGQC ILVSSLDNTV RLMDKDTGEL LNEFKGHQNK EYKLDSCLNH
TDTHVISGSE DGSIHFWDLI EAKLIFSLEK AHKGVAYSLS YHPKDSCLLS ASSDGEVKVW
HEKEWEPS
//
