ID A7SM36_NEMVE Unreviewed; 477 AA.
AC A7SM36;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Agenet-like domain-containing protein {ECO:0000259|PROSITE:PS51641};
GN ORFNames=NEMVEDRAFT_v1g214383 {ECO:0000313|EMBL:EDO35217.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO35217.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO35217.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469705; EDO35217.1; -; Genomic_DNA.
DR RefSeq; XP_001627317.1; XM_001627267.1.
DR AlphaFoldDB; A7SM36; -.
DR STRING; 45351.A7SM36; -.
DR EnsemblMetazoa; EDO35217; EDO35217; NEMVEDRAFT_v1g214383.
DR HOGENOM; CLU_572807_0_0_1; -.
DR InParanoid; A7SM36; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0036464; C:cytoplasmic ribonucleoprotein granule; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005844; C:polysome; IBA:GO_Central.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IBA:GO_Central.
DR GO; GO:0042803; F:protein homodimerization activity; IBA:GO_Central.
DR GO; GO:0045182; F:translation regulator activity; IBA:GO_Central.
DR GO; GO:0017148; P:negative regulation of translation; IBA:GO_Central.
DR GO; GO:0045727; P:positive regulation of translation; IBA:GO_Central.
DR GO; GO:0043488; P:regulation of mRNA stability; IBA:GO_Central.
DR CDD; cd22426; KH_I_FMR1_FXR_rpt2; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR008395; Agenet-like_dom.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR040148; FMR1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR041560; Tudor_FRM1.
DR PANTHER; PTHR10603; FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN; 1.
DR PANTHER; PTHR10603:SF7; SYNAPTIC FUNCTIONAL REGULATOR FMR1; 1.
DR Pfam; PF05641; Agenet; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR PROSITE; PS51641; AGENET_LIKE; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 60..112
FT /note="Agenet-like"
FT /evidence="ECO:0000259|PROSITE:PS51641"
FT REGION 223..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..330
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..362
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 477 AA; 52607 MW; 4F3FD0613006F5C6 CRC64;
MGLWISSSQS LTPTCLSSLS GYGFMDIGLP PASPSERDID LKDDKSTLFL IACYARYNCP
YVWVYTRADD NEPCGWWLAK IIHKKGEFFV IQYSGWDATF NEIVPRERIR PPNTNGSISR
QMYYKLAKKQ MGILERLKLP EHLMGLAIGA QGANIQQARK LPGVMSIEVD EENCTFNICG
EEVEQMKREK ESLDHQLQNM GISPPTGPSY IPTPAEMRIG TNLMVAPPDS TGSTGRDRAL
TTDSYGGDLS EGMSISTDPG TTARPSTIRI RSSSESDNTE SGRLNSQNAN RRAPTPTSEL
TDIREEGEEH GAHKGSSGEP VKDQRKKPSP WFMSNRKRSN SEGKDDKPNG DGRQHQHNGR
SNQRPDQRSW NQGKAQARHS QQSNRSNKSS SNGTQMRSNS GSLSQNWRKQ EGLKERSGSD
ETEAKPSEVA AEETVAEEKV NSEEKSSVES AEQAGKGTEK KSCDQPEAAD APISAEG
//
