ID A7SME5_NEMVE Unreviewed; 317 AA.
AC A7SME5;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDO35113.1};
DE Flags: Fragment;
GN ORFNames=NEMVEDRAFT_v1g123713 {ECO:0000313|EMBL:EDO35113.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO35113.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO35113.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|RuleBase:RU000363}.
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DR EMBL; DS469708; EDO35113.1; -; Genomic_DNA.
DR RefSeq; XP_001627213.1; XM_001627163.1.
DR AlphaFoldDB; A7SME5; -.
DR STRING; 45351.A7SME5; -.
DR eggNOG; KOG1610; Eukaryota.
DR HOGENOM; CLU_010194_2_0_1; -.
DR InParanoid; A7SME5; -.
DR PhylomeDB; A7SME5; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR GO; GO:0008202; P:steroid metabolic process; IBA:GO_Central.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR43313:SF1; DEHYDROGENASES, SHORT CHAIN; 1.
DR PANTHER; PTHR43313; SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C; 1.
DR Pfam; PF00106; adh_short; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..317
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002715357"
FT NON_TER 317
FT /evidence="ECO:0000313|EMBL:EDO35113.1"
SQ SEQUENCE 317 AA; 35606 MW; 86CD99D1C4E5D3E3 CRC64;
IAVLFVAWLS LKFLPPTRRV GDYHNKYVLV TGCDSGLGRD LAIRLDGMGF HVFGACLTQQ
GKQDLEQTCS KRTVGLLMDV TSHEQIAEAF EQVKRFIHIT PGLWAVYNNA GYMTLAPLEW
FPLDDYKRMA DVNLWGLVDV TKTFLPLVKM ARGRVVNVAS IVGGCLIAGE LTAPYSITKY
GVEAFSDVLR REMLPWGVRV SIIEPQAFKT PLWDNIATKK YMSLWNGLDP EMKKEYGEKF
VEEDVAGLRK YMDMSSTAFY MVVDAAIDAI TSRDPKHRYP VGWNAKVVSI LGVLPSGWTD
AFLWTTWPRP SPLGAKK
//
